1-(2-Chlorophenyl)-3-methylurea

Base Information

Chemical Name:1-(2-Chlorophenyl)-3-methylurea
CAS No.:15500-96-6
Molecular Formula:C₈H₉ClN₂O
Molecular Weight:184.625
Hs Code.:2924299090
Mol file:15500-96-6.mol

Synonyms:Urea,1-(o-chlorophenyl)-3-methyl- (8CI); 1-(2-Chlorophenyl)-3-methylurea;1-Methyl-3-(2-chlorophenyl)urea; N-Methyl-N1-(2-chlorophenyl)urea;N-Methyl-N'-(2-chlorophenyl)urea

Suppliers and Price of 1-(2-Chlorophenyl)-3-methylurea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
1-(2-CHLOROPHENYL)-3-METHYLUREA Aldrich
250mg
$ 57.00

American Custom Chemicals Corporation
1-(2-CHLOROPHENYL)-3-METHYLUREA 95.00%
5MG
$ 498.39

Total 7 raw suppliers

Chemical Property of 1-(2-Chlorophenyl)-3-methylurea

Chemical Property:

Vapor Pressure:0.0123mmHg at 25°C
Boiling Point:260.3°Cat760mmHg
Flash Point:111.2°C
PSA：44.62000
Density:1.288g/cm³
LogP:2.36870

Purity/Quality:

97% ^*data from raw suppliers

1-(2-CHLOROPHENYL)-3-METHYLUREA Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(2-Chlorophenyl)-3-methylurea

There total 1 articles about 1-(2-Chlorophenyl)-3-methylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3320-83-0
o-chlorophenyl isocyanate

: 372-09-8
cyanoacetic acid

: 15500-96-6
N-Methyl-N'-(2-chlorophenyl)urea

Guidance literature:: With methylamine;

Reference yield:

: 15500-96-6
N-Methyl-N'-(2-chlorophenyl)urea

: 6-hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid [6-amino-1-(2-chloro-phenyl)-3-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl]-amide

Guidance literature:: Multi-step reaction with 5 steps

1.1: acetic anhydride / ethyl acetate / 4 h / Heating

2.1: NaOH / H₂O; ethyl acetate / 6 h / 20 °C / pH 10

3.1: sodium nitrite; HCl / H₂O / 2 h

4.1: H₂ / Pd/C / methanol / 1 h

5.1: diphenylphosphoryl chloride; triethylamine / ethyl acetate / 1 h / cooling

5.2: 34 percent / triethylamine / ethyl acetate / 3 h / 20 °C

With hydrogenchloride; sodium hydroxide; hydrogen; acetic anhydride; triethylamine; sodium nitrite; Diphenylphosphinic chloride; palladium on activated charcoal; In methanol; water; ethyl acetate;
DOI:10.1016/j.bmc.2003.09.012

Reference yield:

: 15500-96-6
N-Methyl-N'-(2-chlorophenyl)urea

: 176379-66-1
5,6-diamino-1-(2-chlorophenyl)-3-methyl-2,4 (1H, 3H)-pyrimidinedione

Guidance literature:: Multi-step reaction with 4 steps

1: acetic anhydride / ethyl acetate / 4 h / Heating

2: NaOH / H₂O; ethyl acetate / 6 h / 20 °C / pH 10

3: sodium nitrite; HCl / H₂O / 2 h

4: H₂ / Pd/C / methanol / 1 h

With hydrogenchloride; sodium hydroxide; hydrogen; acetic anhydride; sodium nitrite; palladium on activated charcoal; In methanol; water; ethyl acetate;
DOI:10.1016/j.bmc.2003.09.012