4-[2-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazino]benzoate

Base Information

• Chemical Name: 4-[2-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazino]benzoate
• CAS No.: 314291-25-3
• Molecular Formula: C₁₇H₁₄N₄O₃
• Molecular Weight: 322.323
• Mol file: 314291-25-3.mol

Synonyms:Benzoicacid, 4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)hydrazino]-(9CI)

Chemical Property of 4-[2-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazino]benzoate

Chemical Property:

• Vapor Pressure: 6.86E-11mmHg at 25°C
• Boiling Point: 501.8°Cat760mmHg
• Flash Point: 257.3°C
• Density: g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-[2-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazino]benzoate

There total 3 articles about 4-[2-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazino]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H13ClN4O2 (127811-58-9) → 1-phenyl-3-methyl-4-((4-carboxyphenyl)hydrazono)pyrazol-5-one (314291-25-3)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / 1.5 h / Molecular sieve; Reflux

2: sodium hydroxide / water

3: water; hydrogenchloride

With hydrogenchloride; water; potassium carbonate; sodium hydroxide; In water;

DOI:10.1016/j.cclet.2014.03.045

Reference yield:

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) + edaravone (89-25-8) → 1-phenyl-3-methyl-4-((4-carboxyphenyl)hydrazono)pyrazol-5-one (314291-25-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide; sodium nitrite / water / 20 °C

1.2: 0 - 5 °C

1.3: 3 h / 0 - 5 °C / pH 8.5 - 9

2.1: water; hydrogenchloride

With hydrogenchloride; water; sodium hydroxide; sodium nitrite; In water;

DOI:10.1016/j.cclet.2014.03.045

Reference yield:

C17H13N4O3(1-)*Na(1+) (1621086-60-9) → 1-phenyl-3-methyl-4-((4-carboxyphenyl)hydrazono)pyrazol-5-one (314291-25-3)

Guidance literature:

With hydrogenchloride; water;

DOI:10.1016/j.cclet.2014.03.045

upstream raw materials:

4-amino-benzoic acid

edaravone

C₁₇H₁₃N₄O₃^(1-)*Na⁽¹⁺⁾

C₁₇H₁₃ClN₄O₂