4,4,4-Trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one

Base Information

Chemical Name:4,4,4-Trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one
CAS No.:35443-84-6
Molecular Formula:C11H6F6O
Molecular Weight:268.158
Hs Code.:
NSC Number:160094
DSSTox Substance ID:DTXSID20303686
Nikkaji Number:J1.045.695I

Synonyms:35443-84-6;4,4,4-trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one;NSC160094;DTXSID20303686;NSC-160094;2-Buten-1-one, 4,4,4-trifluoro-1-phenyl-3-(trifluoromethyl)-

Suppliers and Price of 4,4,4-Trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4,4,4-Trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one

Chemical Property:

Vapor Pressure:0.00704mmHg at 25°C
Boiling Point:270°Cat760mmHg
Flash Point:103.2°C
Density:1.363g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:268.03228378
Heavy Atom Count:18
Complexity:316

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C=C(C(F)(F)F)C(F)(F)F

Technology Process of 4,4,4-Trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one

There total 8 articles about 4,4,4-Trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 731-00-0
4,4,4-trifluoro-3-hydroxy-3-methyl-1-phenyl-3-trifluoromethylbutan-1-one

: 35443-84-6
4,4,4-trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one

Guidance literature:: With pyridine; trifluoroacetic anhydride; In diethyl ether; at 0 ℃; for 1h;
DOI:10.1002/prac.19923340304

Reference yield: 85.0%

: 82959-21-5
3,4,4,4-Tetrafluoro-1-phenyl-3-trifluoromethyl-butan-1-one

: 35443-84-6
4,4,4-trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one

Guidance literature:: With base;
DOI:10.1016/S0040-4039(00)87135-X

Reference yield: 51.0%

: 3,4,4,4-tetrafluoro-1-phenyl-3-(trifluoromethyl)butan-1-ol

: 35443-84-6
4,4,4-trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one

Guidance literature:: 3,4,4,4-tetrafluoro-1-phenyl-3-(trifluoromethyl)butan-1-ol; With silica gel; pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 24h; Schlenk technique;

With 1,4-diaza-bicyclo[2.2.2]octane; In acetonitrile; at 20 ℃; for 7h;
DOI:10.1055/a-1674-6564