N-[4-(2-bromoacetyl)phenyl]methanesulfonamide

Base Information

Chemical Name:N-[4-(2-bromoacetyl)phenyl]methanesulfonamide
CAS No.:5577-42-4
Molecular Formula:C12H16N2O2
Molecular Weight:292.153
Hs Code.:2935009090
European Community (EC) Number:803-877-5
Mol file:5577-42-4.mol

Synonyms:N-[4-(2-bromoacetyl)phenyl]methanesulfonamide;5577-42-4;N-(4-(2-Bromoacetyl)phenyl)methanesulfonamide;Methanesulfonamide, N-[4-(bromoacetyl)phenyl]-;SCHEMBL3847673;IOXQOFCRSXSIQZ-UHFFFAOYSA-N;4-methanesulphonamidophenacyl bromide;4'-(2-Bromoacetyl)methanesulfonanilide;4-(methylsulfonylamino)phenacyl bromide;N-[4-bromoacetylphenyl]methanesulphonamide;CS-0257431;N-[4-(bromoacetyl)phenyl]methanesulphonamide;EN300-67255

Suppliers and Price of N-[4-(2-bromoacetyl)phenyl]methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide
100mg
$ 1100.00

TRC
N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide
10mg
$ 140.00

Biosynth Carbosynth
N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide
100 mg
$ 1365.00

Biosynth Carbosynth
N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide
5 mg
$ 124.90

Biosynth Carbosynth
N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide
50 mg
$ 751.00

Biosynth Carbosynth
N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide
25 mg
$ 413.00

Biosynth Carbosynth
N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide
10 mg
$ 227.20

Total 8 raw suppliers

Chemical Property of N-[4-(2-bromoacetyl)phenyl]methanesulfonamide

Chemical Property:

Vapor Pressure:2.11E-07mmHg at 25°C
Boiling Point:424.2°Cat760mmHg
Flash Point:210.3°C
PSA：45.06000
Density:1.2g/cm³
LogP:1.81060
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:290.95648
Heavy Atom Count:15
Complexity:315

Purity/Quality:

98%min ^*data from raw suppliers

N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)NC1=CC=C(C=C1)C(=O)CBr
Uses A methanesulfonamide analogue of Rofecoxib as COX inhibitors.

Technology Process of N-[4-(2-bromoacetyl)phenyl]methanesulfonamide

There total 14 articles about N-[4-(2-bromoacetyl)phenyl]methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 5317-89-5
4'-(methylsulfonylamino)acetophenone

: 5577-42-4
N-[4-(2-bromoacetyl)phenyl]methanesulfonamide

Guidance literature:: With bromine; acetic acid; at 55 ℃; for 0.25h; regiospecific reaction;
DOI:10.1021/op970039x

Reference yield:

: 99-92-3
p-aminobenzophenone

: 5577-42-4
N-[4-(2-bromoacetyl)phenyl]methanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / CH₂Cl₂ / 3 h / 25 °C

2: 81 percent / bromine; AlCl₃ / CHCl₃ / 0.5 h / 0 °C

With aluminium trichloride; bromine; triethylamine; In dichloromethane; chloroform;
DOI:10.1016/j.bmc.2006.10.023