(2-{[2-(HYDROXYMETHYL)PHENYL]THIO}PHENYL)METHANOL

Base Information

• Chemical Name: (2-{[2-(HYDROXYMETHYL)PHENYL]THIO}PHENYL)METHANOL
• CAS No.: 38059-09-5
• Molecular Formula: C14H14O2S
• Molecular Weight: 246.33
• Hs Code.: 2930909090
• Mol file: 38059-09-5.mol

Synonyms:(2-{[2-(HYDROXYMETHYL)PHENYL]THIO}PHENYL)METHANOL;BIS(2-HYDROXYMETHYLPHENYL)SULFIDE;[2-[(2-methylolphenyl)thio]phenyl]methanol;[2-[2-(hydroxymethyl)phenyl]sulfanylphenyl]methanol

Chemical Property of (2-{[2-(HYDROXYMETHYL)PHENYL]THIO}PHENYL)METHANOL

Chemical Property:

• Vapor Pressure: 5.09E-07mmHg at 25°C
• Refractive Index: 1.673
• Boiling Point: 397.1 °C at 760 mmHg
• Flash Point: 192.9 °C
• PSA: 65.76000
• Density: 1.28 g/cm³
• LogP: 2.82240

Purity/Quality:

99% ^*data from raw suppliers

(2-[[2-(HYDROXYMETHYL)PHENYL]THIO]PHENYL)METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-{[2-(HYDROXYMETHYL)PHENYL]THIO}PHENYL)METHANOL

There total 13 articles about (2-{[2-(HYDROXYMETHYL)PHENYL]THIO}PHENYL)METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,2'-Thiobenzoesaeure-dimethylester (49590-24-1) → bis(hydroxymethylphenyl)sulfide (38059-09-5)

Guidance literature:

2,2'-Thiobenzoesaeure-dimethylester; With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 16h;

With water; sodium sulfate; In tetrahydrofuran; diethyl ether; Product distribution / selectivity;

Reference yield: 95.0%

2,2'-thiodibenzoic acid (22219-02-9) → bis(hydroxymethylphenyl)sulfide (38059-09-5)

Guidance literature:

2,2'-thiodibenzoic acid; With borane-THF; In tetrahydrofuran; at 20 ℃; for 16h;

With methanol; water; In tetrahydrofuran; Product distribution / selectivity;

Reference yield: 52.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + diphenyl sulfide (139-66-2) → bis(hydroxymethylphenyl)sulfide (38059-09-5)

Guidance literature:

diphenyl sulfide; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; at 0 ℃; for 24h;

formaldehyd; In hexane; for 48h; Reflux;

DOI:10.1016/j.poly.2011.11.053

upstream raw materials:

formaldehyd

thianthrene-5-oxide

2,2'-Thiobenzoesaeure-dimethylester

water

Downstream raw materials:

[2-(2-Mercaptomethyl-phenylsulfanyl)-phenyl]-methanethiol

2-(2-((6-carboxymethylphenyl)thio)phenyl)acetic acid

2-(2-((6-cyanomethylphenyl)thio)phenyl)acetonitrile

C₁₄H₁₀O₃S

Refernces

• 1、 Martinez-Otero, Diego,Alvarado-Rodriguez, Jose G.,Cruz-Borbolla, Julian,Andrade-Lopez, Noemi,Pandiyan, Thangarasu,Moreno-Esparza, Rafael,Flores-Alamo, Marcos,Cantillo-Castillo, Jesus. "Study on the intramolecular transannular chalcogen-tin interactions in dithiastannecine compounds". experimental part. p. 367 - 377. Retrieved 2012/03/13.
• 2、 Rachwalski, Michal,Kwiatkowska, Malgorzata,Drabowicz, Jozef,Klos, Marcin,Wieczorek, Wanda M.,Szyrej, Malgorzata,Sieron, Leslaw,Kielbasinski, Piotr. "Enzyme-promoted desymmetrization of bis(2-hydroxymethylphenyl) sulfoxide as a route to tridentate chiral catalysts". . p. 2096 - 2101. Retrieved 2008/12/22.