(-)-cubenol

Base Information

Chemical Name:(-)-cubenol
CAS No.:21284-22-0
Molecular Formula:C₁₅H₂₆O
Molecular Weight:222.371
Hs Code.:

Synonyms:10bH-Cadin-4-en-1-ol (8CI);4a(2H)-Naphthalenol, 1,3,4,5,6,8a-hexahydro-4,7-dimethyl-1-(1-methylethyl)-,[1S-(1a,4b,4ab,8aa)]-; (-)-Cubenol; Cubenol

Suppliers and Price of (-)-cubenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Cubenol
10mg
$ 1420.00

Total 18 raw suppliers

Chemical Property of (-)-cubenol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:303.4°Cat760mmHg
PKA:14.94±0.70(Predicted)
Flash Point:128.3°C
PSA：20.23000
Density:0.952g/cm³
LogP:0.16310

Purity/Quality:

99% ,98%,Electron Grade , ^*data from raw suppliers

Cubenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Cubenol was used for biological study of antioxidant and antimicrobial activity and comparison of cinnamon leaf and bark essential oils and oleoresins. Cubenol was one of the major components of essential oils isolated from the aerial parts of Artemisia absinthium, Artemisia santonicum and Artemisia spicigera.

Technology Process of (-)-cubenol

There total 19 articles about (-)-cubenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 1.0%

: 38230-60-3
4-epi-cubebil

: 19912-67-5,21284-22-0,38757-58-3,68199-14-4,73365-77-2,81939-29-9
cubenol

: 19912-67-5
1–epi–cubenol

: 483-76-1,13061-82-0,16729-01-4,20085-20-5,60305-17-1,73365-79-4
delta-cadinene

: 41929-05-9
(1R,10R)-zonarene

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 0.5h; Ambient temperature;
DOI:10.1246/bcsj.54.2366

Reference yield:

: 60796-18-1
4-isopropyl-7-methyl-octa-5t,7-dienal

: 19912-67-5,21284-22-0,38757-58-3,68199-14-4,73365-77-2,81939-29-9
(+/-)-epicubenol

Guidance literature:: Multi-step reaction with 8 steps

1: 90 percent / tetrahydrofuran / 1 h / Ambient temperature

2: periodinane / CH₂Cl₂

3: benzene / 2 h / 120 °C / sealed tube

4: 15 percent / (Ph₃P)3RhCl / 0.08 h / 93 °C

5: 1.) LHMDS; 2.) Et₃N / 1.) THF, -78 deg C, 15 min; RT, 16 h; 2.) THF, RT, 10 min

6: 1.) m-CPBA; 2.) aq 1N HCl / 1.) CH₂Cl₂, RT, 1 h; 2.) acetonitrile

7: 78 percent / NaH / dimethylsulfoxide / 5 h / Ambient temperature

8: NaBH₄, CoCl₂*6H₂O / ethanol / 14 h / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; sodium hydride; Dess-Martin periodane; triethylamine; 3-chloro-benzenecarboperoxoic acid; cobalt(II) chloride; lithium hexamethyldisilazane; Wilkinson's catalyst; In tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide; benzene;
DOI:10.1016/S0040-4039(00)73497-6

Reference yield:

: (E)-6-Isopropyl-9-methyl-deca-7,9-dien-1-yn-3-ol

: 19912-67-5,21284-22-0,38757-58-3,68199-14-4,73365-77-2,81939-29-9
(+/-)-epicubenol

Guidance literature:: Multi-step reaction with 7 steps

1: periodinane / CH₂Cl₂

2: benzene / 2 h / 120 °C / sealed tube

3: 15 percent / (Ph₃P)3RhCl / 0.08 h / 93 °C

4: 1.) LHMDS; 2.) Et₃N / 1.) THF, -78 deg C, 15 min; RT, 16 h; 2.) THF, RT, 10 min

5: 1.) m-CPBA; 2.) aq 1N HCl / 1.) CH₂Cl₂, RT, 1 h; 2.) acetonitrile

6: 78 percent / NaH / dimethylsulfoxide / 5 h / Ambient temperature

7: NaBH₄, CoCl₂*6H₂O / ethanol / 14 h / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; sodium hydride; Dess-Martin periodane; triethylamine; 3-chloro-benzenecarboperoxoic acid; cobalt(II) chloride; lithium hexamethyldisilazane; Wilkinson's catalyst; In ethanol; dichloromethane; dimethyl sulfoxide; benzene;
DOI:10.1016/S0040-4039(00)73497-6