(2,4,6-Trichloro-3,5-difluorophenyl)hydrazine

Base Information

• Chemical Name: (2,4,6-Trichloro-3,5-difluorophenyl)hydrazine
• CAS No.: 7632-66-8
• Molecular Formula: C6H3 Cl3 F2 N2
• Molecular Weight: 247.4572
• NSC Number: 109623
• DSSTox Substance ID: DTXSID90296495
• Wikidata: Q82037120
• Mol file: 7632-66-8.mol

Synonyms:(2,4,6-trichloro-3,5-difluorophenyl)hydrazine;7632-66-8;NSC109623;SCHEMBL10618055;DTXSID90296495;MFCD30597045;NSC-109623

Chemical Property of (2,4,6-Trichloro-3,5-difluorophenyl)hydrazine

Chemical Property:

• Vapor Pressure: 0.0271mmHg at 25°C
• Boiling Point: 246.5°Cat760mmHg
• Flash Point: 102.9°C
• Density: 1.763g/cm³
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 245.932988
• Heavy Atom Count: 13
• Complexity: 169

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1(=C(C(=C(C(=C1Cl)F)Cl)F)Cl)NN

Technology Process of (2,4,6-Trichloro-3,5-difluorophenyl)hydrazine

There total 2 articles about (2,4,6-Trichloro-3,5-difluorophenyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,3,5-trichlorotrifluorobenzene (319-88-0) → (2,4,6-trichloro-3,5-difluorophenyl)hydrazine (7632-66-8)

Guidance literature:

With hydrazine hydrate; In ethanol; for 1h; Reflux;

DOI:10.1016/j.jfluchem.2018.06.011

Reference yield:

→ (2,4,6-trichloro-3,5-difluorophenyl)hydrazine (7632-66-8)

Guidance literature:

By refluxing 95percent EtOH solution of /BRN= 958307/ and NH2NH2*H2O;

Reference yield:

1-(4-amino-2,3,5,6-tetrafluorophenyl)ethanone (914221-69-5) + (2,4,6-trichloro-3,5-difluorophenyl)hydrazine (7632-66-8) → (E)-2,3,5,6-tetrafluoro-4-(1-(2-(2,4,6-trichloro-3,5-difluorophenyl)hydrazono)ethyl)aniline + (Z)-2,3,5,6-tetrafluoro-4-(1-(2-(2,4,6-trichloro-3,5-difluorophenyl)hydrazono)ethyl)aniline

Guidance literature:

With magnesium sulfate; toluene-4-sulfonic acid; In toluene; for 23h; Overall yield = 95 %; Reflux;

DOI:10.1016/j.jfluchem.2018.06.011

upstream raw materials:

1,3,5-trichlorotrifluorobenzene