2-Demethylcolchicine

Base Information

Chemical Name:2-Demethylcolchicine
CAS No.:7336-36-9
Molecular Formula:C21H24NO6
Molecular Weight:385.417
Hs Code.:
NSC Number:180533
UNII:V9U19L3N0J
DSSTox Substance ID:DTXSID90223605
Nikkaji Number:J118.412A
Wikidata:Q27291711
Metabolomics Workbench ID:121644
ChEMBL ID:CHEMBL1080
Mol file:7336-36-9.mol

Synonyms:2-Demethylcolchicine;2-Demethyl Colchicine;102491-80-5;O2-Demethylcolchicine;7336-36-9;Colchicine, O(2)-demethyl-;2-O-demethyl colchicine;Alkaloid CC 6, from Colchicum cornigerum;O(sup 2)-Demethylcolchicine;NSC 180533;Colchicine, 3-demethyl-;2-DESMETHYLCOLCHICIN;CHEMBL1080;UNII-V9U19L3N0J;N-[(7S)-2-hydroxy-1,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide;V9U19L3N0J;Colchicine, 3-demethyl- (7CI);NSC-180533;COLCHICINE, O(sup 2)-DEMETHYL-;Acetamide, N-(5,6,7,9-tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S);Acetamide, N-(5,6,7,9-tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-;(-)-2-Demethylcolchicine;ACETAMIDE, N-((7S)-5,6,7,9-TETRAHYDRO-2-HYDROXY-1,3,10-TRIMETHOXY-9-OXOBENZO(A)HEPTALEN-7-YL)-;Acetamide, N-(5,6,7,9-tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-;Acetamide, N-[(7S)-5,6,7,9-tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-;2-dimethylcolchicine;SCHEMBL2007529;DTXSID90223605;BDBM50157479;NSC180533;AKOS030254275;LS-54684;J-000700;Q27291711;N-(2-Hydroxy-1,3,10-trimethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide;Acetamide,6,7,9-tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-;N-((S)-2-Hydroxy-1,3,10-trimethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide

Suppliers and Price of 2-Demethylcolchicine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Demethylcolchicine
10mg
$ 389.00

Total 11 raw suppliers

Chemical Property of 2-Demethylcolchicine

Chemical Property:

Melting Point:125°C
Refractive Index:1.5614 (estimate)
Boiling Point:766.1°Cat760mmHg
Flash Point:417.1°C
PSA：94.09000
Density:1.31g/cm³
LogP:2.95950
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:385.15253745
Heavy Atom Count:28
Complexity:724

Purity/Quality:

99% ^*data from raw suppliers

2-Demethylcolchicine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)O)OC
Isomeric SMILES:CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)O)OC

Technology Process of 2-Demethylcolchicine

There total 5 articles about 2-Demethylcolchicine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%