α-Methyl-2-piperidineMethanol

Base Information

• Chemical Name: α-Methyl-2-piperidineMethanol
• CAS No.: 54160-32-6
• Molecular Formula: C7H15NO
• Molecular Weight: 129.202
• Mol file: 54160-32-6.mol

Synonyms:2-Piperidinemethanol, α-methyl-;1-piperidin-2-ylethanol;

Chemical Property of α-Methyl-2-piperidineMethanol

Chemical Property:

• Vapor Pressure: 0.0527mmHg at 25°C
• Boiling Point: 207.4°Cat760mmHg
• PKA: 15.15±0.20(Predicted)
• Flash Point: 82.8°C
• PSA: 32.26000
• Density: 0.952g/cm³
• LogP: 0.83810
• Solubility.: Dichloromethane

Purity/Quality:

99%min ^*data from raw suppliers

α-Methyl-2-piperidinemethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: α-Methyl-2-piperidineMethanol can be used in the preparation of substances with herbicidal activity.

Technology Process of α-Methyl-2-piperidineMethanol

There total 1 articles about α-Methyl-2-piperidineMethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetylpyridine (1122-62-9) → α-methyl-2-piperidylcarbinol (54160-32-6) + 1-(pyridine-2-yl)ethanol (20988-55-0,18728-61-5,27911-63-3,59042-90-9) + 2-acetylpiperidine (97073-22-8,206534-53-4,773016-40-3)

Guidance literature:

With hydrogen; In tetrahydrofuran; at 30 ℃; for 1h; under 3750.38 Torr; Catalytic behavior; Autoclave; Glovebox;

DOI:10.1016/j.jcat.2017.08.010

Reference yield:

α-methyl-2-piperidylcarbinol (54160-32-6) → 2-(2-Chloroethyl)piperidine Hydrochloride (60012-49-9)

Guidance literature:

With hydrogenchloride; thionyl chloride; In 1,4-dioxane; chloroform;

Reference yield:

α-methyl-2-piperidylcarbinol (54160-32-6) → 1-(3,4,5,6-tetrahydro-2-pyridyl)-1-ethanone (27300-27-2)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; Inert atmosphere;

upstream raw materials:

2-acetylpyridine

Downstream raw materials:

1-Methyl-2-acetylpiperidine

1-Methyl-2-ethynylpiperidine

1-Methyl-2-(3'-hydroxy-3',3'-diphenylpropyn-1'-yl)piperidine methiodide

1-Methyl-2-(3'-hydroxy-3',3'-diphenylpropyn-1'-yl)piperidine

Refernces