(2R)-2-(1,3-dioxoisoindol-2-yl)propanoic acid

Base Information

Chemical Name:(2R)-2-(1,3-dioxoisoindol-2-yl)propanoic acid
CAS No.:29588-83-8
Molecular Formula:C11H9 N O4
Molecular Weight:219.197
Hs Code.:
European Community (EC) Number:826-003-4
Nikkaji Number:J231.822I
Mol file:29588-83-8.mol

Synonyms:29588-83-8;(R)-2-(1,3-DIOXOISOINDOLIN-2-YL)PROPANOIC ACID;(2R)-2-(1,3-dioxoisoindol-2-yl)propanoic acid;2H-Isoindole-2-acetic acid, 1,3-dihydro-a-methyl-1,3-dioxo-, (aR)-;SCHEMBL7399848;MFCD24479562;EN300-247943;N12004;(R)-2-(1,3-DIOXOISOINDOLIN-2-YL)PROPANOICACID;(2R)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoic acid

Suppliers and Price of (2R)-2-(1,3-dioxoisoindol-2-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (2R)-2-(1,3-dioxoisoindol-2-yl)propanoic acid

Chemical Property:

Boiling Point:407.9°Cat760mmHg
Flash Point:200.5°C
Density:1.467g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:219.05315777
Heavy Atom Count:16
Complexity:328

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)O)N1C(=O)C2=CC=CC=C2C1=O
Isomeric SMILES:C[C@H](C(=O)O)N1C(=O)C2=CC=CC=C2C1=O

Technology Process of (2R)-2-(1,3-dioxoisoindol-2-yl)propanoic acid

There total 4 articles about (2R)-2-(1,3-dioxoisoindol-2-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 85-44-9
phthalic anhydride

: 338-69-2,25191-17-7,18875-37-1
D-Alanine

: 29588-83-8
(R)-N-phthaloylalanine

Guidance literature:: for 0.05h; microwave irradiation;

Reference yield:

: 85-44-9
phthalic anhydride

: 56-41-7,25191-17-7,18875-37-1
L-alanine

: 4192-28-3,19506-87-7,21860-84-4,29588-83-8
N-phthalyl-L-alanine

Guidance literature:: DOI:10.1007/BF00959578

Reference yield:

: 73365-03-4,23101-87-3
2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanal

: 29588-83-8
(R)-N-phthaloylalanine

: 4192-28-3
Phth-L-Ala-OH

Guidance literature:: With 9-oxyl-9-azabicyclo<3.3.1>nonan-3-one; oxygen; nitric acid; sodium nitrite; In water; acetonitrile; at 23 ℃; for 8h; under 760.051 Torr; Overall yield = 87 %; Overall yield = 191 mg; enantioselective reaction; Sealed tube;
DOI:10.1021/acs.orglett.6b01598