1-(4-Methoxyphenyl)pyrrolidin-2-one

Base Information

Chemical Name:1-(4-Methoxyphenyl)pyrrolidin-2-one
CAS No.:30425-47-9
Molecular Formula:C11H13 N O2
Molecular Weight:191.23
Hs Code.:2933790090
European Community (EC) Number:250-191-1
DSSTox Substance ID:DTXSID20184513
Nikkaji Number:J249.986J
Wikidata:Q83055423
ChEMBL ID:CHEMBL1649591
Mol file:30425-47-9.mol

Synonyms:1-(4-Methoxyphenyl)pyrrolidin-2-one;30425-47-9;EINECS 250-191-1;Bionet2_000141;SCHEMBL609306;CHEMBL1649591;DTXSID20184513;HMS1364G09;1-(4-Methoxyphenyl)-2-pyrrolidone;MFCD00138488;N-(4-methoxyphenyl)pyrrolidin-2-one;STK670401;1-(4-methoxyphenyl)-2-pyrrolidinone;AKOS002980553;CS-0206050;EU-0084166;FT-0717863;1-(4-METHOXY-PHENYL)-PYRROLIDIN-2-ONE;7B-110;SR-01000510287;SR-01000510287-1

Suppliers and Price of 1-(4-Methoxyphenyl)pyrrolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4-Methoxyphenyl)-2-pyrrolidinone
2.5g
$ 525.00

Medical Isotopes, Inc.
1-(4-Methoxyphenyl)-2-pyrrolidinone
250 mg
$ 550.00

Matrix Scientific
1-(4-Methoxyphenyl)pyrrolidin-2-one
500mg
$ 315.00

Crysdot
1-(4-Methoxyphenyl)pyrrolidin-2-one 97%
1g
$ 320.00

Crysdot
1-(4-Methoxyphenyl)pyrrolidin-2-one 97%
5g
$ 904.00

American Custom Chemicals Corporation
1-(4-METHOXYPHENYL)-2-PYRROLIDINONE 95.00%
1G
$ 808.50

American Custom Chemicals Corporation
1-(4-METHOXYPHENYL)-2-PYRROLIDINONE 95.00%
0.5G
$ 726.00

AK Scientific
1-(4-Methoxyphenyl)pyrrolidin-2-one
500mg
$ 475.00

Total 8 raw suppliers

Chemical Property of 1-(4-Methoxyphenyl)pyrrolidin-2-one

Chemical Property:

Vapor Pressure:4.35E-07mmHg at 25°C
Boiling Point:414.7°Cat760mmHg
Flash Point:204.6°C
PSA：29.54000
Density:1.162g/cm³
LogP:1.88700
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:191.094628657
Heavy Atom Count:14
Complexity:209

Purity/Quality:

98%min ^*data from raw suppliers

1-(4-Methoxyphenyl)-2-pyrrolidinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N2CCCC2=O
Uses 1-(4-Methoxyphenyl)-2-pyrrolidinone is a useful synthetic intermediate in the synthesis of Clanobutin (C558000); a compound that inhibits gluconeogenesis in isolated perfused rat livers. It is a choleretic and digestion-stimulating agent for animals.

Technology Process of 1-(4-Methoxyphenyl)pyrrolidin-2-one

There total 24 articles about 1-(4-Methoxyphenyl)pyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 616-45-5
2-pyrrolidinon

: 696-62-8
para-iodoanisole

: 30425-47-9
N-(4-methoxyphenyl)-2-pyrrolidinone

Guidance literature:: With copper; potassium carbonate; In N,N-dimethyl-formamide; at 150 ℃; for 18h; Inert atmosphere;
DOI:10.1021/ol8017209

Reference yield: 96.0%

: 616-45-5
2-pyrrolidinon

: 623-12-1
4-chloromethoxybenzene

: 30425-47-9
N-(4-methoxyphenyl)-2-pyrrolidinone

Guidance literature:: With potassium phosphate; [(π-allyl)Pd(tBuBrettPhos)]OTf; In tert-butyl alcohol; at 110 ℃; for 3h; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.5b01005