3-(Naphthalen-1-yl)-3-oxopropanoic acid

Base Information

Chemical Name:3-(Naphthalen-1-yl)-3-oxopropanoic acid
CAS No.:76103-97-4
Molecular Formula:C13H10O3
Molecular Weight:214.221
Hs Code.:
NSC Number:126798
DSSTox Substance ID:DTXSID70298891
Wikidata:Q82040990

Synonyms:3-(naphthalen-1-yl)-3-oxopropanoic acid;76103-97-4;NSC 126798;naphtoylacetic acid;NSC126798;SCHEMBL3371176;DTXSID70298891;NSC-126798

Suppliers and Price of 3-(Naphthalen-1-yl)-3-oxopropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-(Naphthalen-1-yl)-3-oxopropanoic acid

Chemical Property:

Vapor Pressure:5.87E-09mmHg at 25°C
Boiling Point:452°Cat760mmHg
Flash Point:241.3°C
Density:1.288g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:214.062994177
Heavy Atom Count:16
Complexity:285

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC=C2C(=O)CC(=O)O

Technology Process of 3-(Naphthalen-1-yl)-3-oxopropanoic acid

There total 2 articles about 3-(Naphthalen-1-yl)-3-oxopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 226931-47-1
3-(naphthalen-1-yl)-3-carbonylpropionic acid methyl ester

: 76103-97-4
3-(naphthalene-1-yl)-3-oxopropanoic acid

Guidance literature:: 3-(naphthalen-1-yl)-3-carbonylpropionic acid methyl ester; With sodium hydroxide; for 12h;

With hydrogenchloride; In water; at 0 ℃;
DOI:10.1039/d1ob01555a

Reference yield:

: 941-98-0
1'-naphthacetophenone

: 76103-97-4
3-(naphthalene-1-yl)-3-oxopropanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / 1,4-dioxane / 0.5 h / 20 °C / Inert atmosphere

1.2: Reflux; Inert atmosphere

2.1: sodium hydroxide / 12 h

2.2: 0 °C

With sodium hydride; sodium hydroxide; In 1,4-dioxane;
DOI:10.1039/d1ob01555a

Reference yield: 89.0%

: 76103-97-4
3-(naphthalene-1-yl)-3-oxopropanoic acid

: 59762-59-3
2-(1-benzyl-2-oxo-1,2-dihydro-indol-3-ylidene)malononitrile

: 2-(1-benzyl-3-(2-(naphthalen-1-yl)-2-oxoethyl)-2-oxoindolin-3-yl)malononitrile

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In neat (no solvent); for 0.166667h; Milling; Green chemistry;
DOI:10.1016/j.tet.2016.12.070