Antiarone f

Base Information

• Chemical Name: Antiarone f
• CAS No.: 130756-19-3
• Molecular Formula: C22H24 O6
• Molecular Weight: 384.4224
• Mol file: 130756-19-3.mol

Synonyms:4H-1-Benzopyran-4-one,2-[3,4-dimethoxy-2-(3-methyl-2-butenyl)phenyl]-2,3-dihydro-5,7-dihydroxy-(9CI); 4H-1-Benzopyran-4-one,2-[3,4-dimethoxy-2-(3-methyl-2-butenyl)phenyl]-2,3-dihydro-5,7-dihydroxy-, (?à)-; (?à)-Antiarone F; Antiarone F

Chemical Property of Antiarone f

Chemical Property:

• Vapor Pressure: 8.55E-14mmHg at 25°C
• Boiling Point: 574.4°C at 760 mmHg
• Flash Point: 199.6°C
• PSA: 85.22000
• Density: 1.245g/cm³
• LogP: 4.33020

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Antiarone f

There total 8 articles about Antiarone f which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-[3,4-Dimethoxy-2-(3-methyl-but-2-enyl)-phenyl]-5,7-bis-methoxymethoxy-chroman-4-one (157027-27-5) → antiarone F (130756-19-3)

Guidance literature:

With hydrogenchloride; In methanol; for 0.25h; Heating;

DOI:10.1080/00304949609356517

Reference yield:

2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) → antiarone F (130756-19-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 63 percent / K₂CO₃ / acetone / 0.5 h / Heating

2: 89 percent / KOH / ethanol; H₂O / Ambient temperature

3: 80 percent / NaOAc / ethanol; H₂O / 24 h / Heating

4: 92 percent / 3 N aq. HCl / methanol / 0.25 h / Heating

With hydrogenchloride; potassium hydroxide; sodium acetate; potassium carbonate; In methanol; ethanol; water; acetone;

DOI:10.1080/00304949609356517

Reference yield:

2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone (65490-09-7) → antiarone F (130756-19-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 89 percent / KOH / ethanol; H₂O / Ambient temperature

2: 80 percent / NaOAc / ethanol; H₂O / 24 h / Heating

3: 92 percent / 3 N aq. HCl / methanol / 0.25 h / Heating

With hydrogenchloride; potassium hydroxide; sodium acetate; In methanol; ethanol; water;

DOI:10.1080/00304949609356517

upstream raw materials:

2-[3,4-Dimethoxy-2-(3-methyl-but-2-enyl)-phenyl]-5,7-bis-methoxymethoxy-chroman-4-one

2,4,6-trihydroxyacetophenone

2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone

prenyl bromide