N-(2-BroMoethyl)urethane

Base Information

• Chemical Name: N-(2-BroMoethyl)urethane
• CAS No.: 7452-78-0
• Molecular Formula: C5H10 Br N O2
• Molecular Weight: 196.044
• Mol file: 7452-78-0.mol

Synonyms:Carbamicacid, (2-bromoethyl)-, ethyl ester (7CI,8CI,9CI); EthylN-(2-bromoethyl)carbamate; N-(2-Bromoethyl)urethane; NSC 145420

Chemical Property of N-(2-BroMoethyl)urethane

Chemical Property:

• Vapor Pressure: 0.0329mmHg at 25°C
• Boiling Point: 243°C at 760 mmHg
• Flash Point: 100.7°C
• PSA: 38.33000
• Density: 1.435g/cm³
• LogP: 1.51830
• Solubility.: Chloroform, Dichloromethane, Diethyl Ether

Purity/Quality:

99% ^*data from raw suppliers

N-(2-Bromoethyl)urethane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-(2-BroMoethyl)urethane is used in the preparation of chiral carbamate butanoates as pest control agents.

Technology Process of N-(2-BroMoethyl)urethane

There total 4 articles about N-(2-BroMoethyl)urethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

chloroformic acid ethyl ester (541-41-3) + 2-bromoethylamine hydrochloride (58861-74-8) → ethyl N-(2-bromoethyl)carbamate (7452-78-0)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 4 ℃; for 1h;

DOI:10.1021/jm960372b

Reference yield:

N-ethoxycarbonylaziridine (671-51-2) → ethyl N-(2-bromoethyl)carbamate (7452-78-0)

Guidance literature:

With hydrogen bromide;

Reference yield:

ethyl 2-methylsulfonyloxyethylcarbamate (133044-89-0) → ethyl N-(2-bromoethyl)carbamate (7452-78-0)

Guidance literature:

With lithium bromide; In acetone; Heating;

DOI:10.1021/ol702472u

upstream raw materials:

2-bromoethylamine

chloroformic acid ethyl ester

N-ethoxycarbonylaziridine

2-bromoethylamine hydrochloride

Downstream raw materials:

{2-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-carbamic acid ethyl ester

O-Ethyl-N-(2-m-toluidino-ethyl)-urethan

N-Nitroso-N-<2-benzolsulfonyl-aethyl>-urethan

C₁₈H₂₁N₃O₄

Refernces

• 1、 Bhatia, Pramila A.,Brooks, Clint D. W.,Basha, Anwer,Ratajczyk, James D.,Gunn, Bruce P.,Bouska, Jennifer B.,Lanni, Carmine,Young, Patrick R.,Bell, Randy L.,Carter, George W.. "5-Lipoxygenase inhibitors: Synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones". . p. 3938 - 3950. Retrieved 2007/10/03.