N-(3-(Dimethylamino)propyl)-N-((methylamino)carbonyl)-6-(2-propenyl)ergoline-8beta-carboxamide

Base Information

Chemical Name:N-(3-(Dimethylamino)propyl)-N-((methylamino)carbonyl)-6-(2-propenyl)ergoline-8beta-carboxamide
CAS No.:126554-48-1
Molecular Formula:C25H35 N5 O2
Molecular Weight:437.5777
Hs Code.:
DSSTox Substance ID:DTXSID90925591
Mol file:126554-48-1.mol

Synonyms:BRN 6019477;N-(3-(Dimethylamino)propyl)-N-((methylamino)carbonyl)-6-(2-propenyl)ergoline-8beta-carboxamide;126554-48-1;Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((methylamino)carbonyl)-6-(2-propenyl)-,(8-beta)-;DTXSID90925591;C25H35N5O2;LS-64373;N-[3-(Dimethylamino)propyl]-N'-methyl-N-{[6-(prop-2-en-1-yl)ergolin-8-yl]carbonyl}carbamimidic acid

Suppliers and Price of N-(3-(Dimethylamino)propyl)-N-((methylamino)carbonyl)-6-(2-propenyl)ergoline-8beta-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(3-(Dimethylamino)propyl)-N-((methylamino)carbonyl)-6-(2-propenyl)ergoline-8beta-carboxamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.17g/cm³
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:437.27907538
Heavy Atom Count:32
Complexity:698

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC(=O)N(CCCN(C)C)C(=O)C1CC2C(CC3=CNC4=CC=CC2=C34)N(C1)CC=C
Isomeric SMILES:CNC(=O)N(CCCN(C)C)C(=O)[C@@H]1CC2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)CC=C

Technology Process of N-(3-(Dimethylamino)propyl)-N-((methylamino)carbonyl)-6-(2-propenyl)ergoline-8beta-carboxamide

There total 3 articles about N-(3-(Dimethylamino)propyl)-N-((methylamino)carbonyl)-6-(2-propenyl)ergoline-8beta-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 85329-86-8
(6aR,9R,10aR)-7-allyl-N-[3-(dimethylamino)propyl]-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide

: 624-83-9
methyl isocyanate

: 126554-48-1
N-<3-(dimethylamino)propyl>-N-<(methylamino)-carbonyl>-6-(2-propenyl)-ergoline-8β-carboxamide

Guidance literature:: DOI:10.1016/0223-5234(89)90087-1

Reference yield:

: 72821-79-5
methyl (6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

: 126554-48-1
N-<3-(dimethylamino)propyl>-N-<(methylamino)-carbonyl>-6-(2-propenyl)-ergoline-8β-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / acetic acid / Heating

2: 80 percent

In acetic acid;
DOI:10.1016/0223-5234(89)90087-1

Reference yield:

: 109-55-7
1-amino-3-(dimethylamino)propane

: 126554-48-1
N-<3-(dimethylamino)propyl>-N-<(methylamino)-carbonyl>-6-(2-propenyl)-ergoline-8β-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / acetic acid / Heating

2: 80 percent

In acetic acid;
DOI:10.1016/0223-5234(89)90087-1