11alpha-Acetoxyprogesterone

Base Information

Chemical Name:11alpha-Acetoxyprogesterone
CAS No.:2268-98-6
Molecular Formula:C23H32 O4
Molecular Weight:372.505
Hs Code.:
NSC Number:82850,63534
DSSTox Substance ID:DTXSID20945343
Nikkaji Number:J149.405H
Wikidata:Q82922671
Mol file:2268-98-6.mol

Synonyms:2268-98-6;11alpha-Acetoxyprogesterone;11alpha-Hydroxyprogesterone Acetate;11.alpha.-Acetoxyprogesterone;(8S,9S,10R,11R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-11-yl acetate;[(8S,9S,10R,11R,13S,14S,17S)-17-acetyl-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-11-yl] acetate;Pregn-4-ene-3,20-dione, 11-(acetyloxy)-, (11a)-;Pregn-4-ene-3, 11.alpha.-hydroxy-, acetate;MLS002693435;Pregn-4-ene-3, 11-(acetyloxy)-, (11.alpha.)-;Pregn-4-ene-3,20-dione, 11.alpha.-hydroxy-, acetate;Pregn-4-ene-3,20-dione, 11-(acetyloxy)-, (11.alpha.)-;3,20-Dioxopregn-4-en-11-yl acetate;NSC82850;Progesterone acetate;U 5533;Acetoxyprogesterone;SCHEMBL7716451;DTXSID20945343;IWRPVTXREVYBHT-ZQEATNLPSA-N;11+/--Hydroxyprogesterone Acetate;CAA26898;NSC63534;NSC-63534;NSC-82850;11.alpha.-Hydroxyprogesterone Acetate;AKOS024285105;11Alpha-acetoxypregn-4-ene-3,20-dione;Progesterone, 11alpha-hydroxy-, acetate;11.alpha.-acetoxypregn-4-ene-3,20-dione;H0499;4-Pregnen-11.alpha.-ol-3,20-dione Acetate;T72113;11alpha-Hydroxypregn-4-ene-3,20-dione Acetate;3,20-Dioxopregn-4-en-11-yl acetate, (11.alpha.)-;(8S,9S,10R,11R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-11-ylacetate

Suppliers and Price of 11alpha-Acetoxyprogesterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
11α-Acetoxyprogesterone
10g
$ 405.00

Crysdot
(8S,9S,10R,11R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-11-ylacetate 95+%
1g
$ 121.00

Chem-Impex
11α-Hydroxyprogesteroneacetate,98%(GC) 98%(GC)
1G
$ 103.04

American Custom Chemicals Corporation
11ALPHA-HYDROXYPROGESTERONE ACETATE 95.00%
1G
$ 676.96

AK Scientific
11alpha-Acetoxyprogesterone
1g
$ 178.00

Total 19 raw suppliers

Chemical Property of 11alpha-Acetoxyprogesterone

Chemical Property:

Vapor Pressure:6.54E-10mmHg at 25°C
Melting Point:177oC
Boiling Point:494.3°Cat760mmHg
Flash Point:213.5°C
PSA：60.44000
Density:1.14g/cm³
LogP:4.26510
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:372.23005950
Heavy Atom Count:27
Complexity:722

Purity/Quality:

98%,99%, ^*data from raw suppliers

11α-Acetoxyprogesterone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(=O)C1CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)OC(=O)C)C
Isomeric SMILES:CC(=O)[C@H]1CC[C@@H]2[C@@]1(C[C@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)OC(=O)C)C
Uses metabolite of progesterone

Technology Process of 11alpha-Acetoxyprogesterone

There total 1 articles about 11alpha-Acetoxyprogesterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57-83-0
Progesterone

: 600-48-6
6β,11α-dihydroxyprogesterone

: 80-75-1,22847-91-2
11-alpha-hydroxyprogesterone

: 2268-98-6
11α-acetoxyprogesterone

Guidance literature:: In dimethyl sulfoxide; at 37 ℃; for 216h; Microbiological reaction;
DOI:10.1016/j.steroids.2019.05.013

Reference yield: 15.0%

: 2268-98-6
11α-acetoxyprogesterone

: 80-75-1,22847-91-2
11-alpha-hydroxyprogesterone

Guidance literature:: With bis(tri-n-butyltin)oxide; In toluene; at 110 ℃; for 70h;
DOI:10.1016/0040-4039(95)00616-K

Reference yield:

: 2268-98-6
11α-acetoxyprogesterone

: 14418-12-3
4-Hydroxy-11α-acetoxy-Δ^1.4-pregnadiendion-(3.20)

Guidance literature:: Multi-step reaction with 2 steps

1: DDQ / benzene

2: OsO₄, Py

With pyridine; osmium(VIII) oxide; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In benzene;
DOI:10.1016/0040-4020(67)85047-6