2,3,4-Trichlorothiophene

Base Information

• Chemical Name: 2,3,4-Trichlorothiophene
• CAS No.: 17249-78-4
• Molecular Formula: C4H Cl3 S
• Molecular Weight: 187.477
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID30938165
• Nikkaji Number: J1.720.188C
• Wikidata: Q82914418
• Mol file: 17249-78-4.mol

Synonyms:2,3,4-Trichlorothiophene;17249-78-4;Thiophene,2,3,4-trichloro-;Thiophene, trichloro-;Thiophene, 2,3,4-trichloro-;trichlorothiophene;2,3,4-trichloro-thiophene;SCHEMBL1177826;DTXSID30938165;AKOS006331887;26761-53-5

Chemical Property of 2,3,4-Trichlorothiophene

Chemical Property:

• Vapor Pressure: 0.257mmHg at 25°C
• Boiling Point: 212°Cat760mmHg
• Flash Point: 105.6°C
• PSA: 28.24000
• Density: 1.633g/cm³
• LogP: 3.70830
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 185.886454
• Heavy Atom Count: 8
• Complexity: 87.4

Purity/Quality:

99% ^*data from raw suppliers

2,3,4-TRICHLOROTHIOPHENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=C(S1)Cl)Cl)Cl

Technology Process of 2,3,4-Trichlorothiophene

There total 6 articles about 2,3,4-Trichlorothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

3,4,5-trichlorothiophene-2-carboxylic acid (26020-48-4) → 2,3,4-trichlorothiophene (17249-78-4)

Guidance literature:

With acetic acid; silver carbonate; In dimethyl sulfoxide; at 120 ℃; for 16h;

DOI:10.1021/ol902482p

Reference yield: 77.0%

2,3,4,5-tetrachlorothiophene (6012-97-1) → 2,3,4-trichlorothiophene (17249-78-4)

Guidance literature:

With n-butyllithium; In diethyl ether;

Reference yield: 66.0%

3,4,5-trichlorothiophene-2-carboxylic acid (26020-48-4) → 2,3,4-trichlorothiophene (17249-78-4) + perchloro-2,2'-bithiophene (34721-65-8)

Guidance literature:

With palladium(II) trifluoroacetate; silver carbonate; In dimethyl sulfoxide; N,N-dimethyl-formamide; at 120 ℃; for 16h; Inert atmosphere;

DOI:10.1039/c0cc01943g

upstream raw materials:

thiophene

2,2,3,4,5-pentachloro-tetrahydro-thiophene

2,3,4,5-tetrachlorothiophene

3,4,5-trichlorothiophene-2-carboxylic acid

Downstream raw materials:

2-acetyl-3,4,5-trichlorothiophene

2,3,4,5-tetrachlorothiophene

3,4-dichlorothiophene

3,4,5-trichlorothiophene-2-carboxylic acid