7alpha,17beta-Dihydroxyandrost-4-en-3-one

Base Information

Chemical Name:7alpha,17beta-Dihydroxyandrost-4-en-3-one
CAS No.:62-83-9
Molecular Formula:C₁₉H₂₈O₃
Molecular Weight:304.43
Hs Code.:
NSC Number:51179
DSSTox Substance ID:DTXSID50977536
Mol file:62-83-9.mol

Synonyms:7-hydroxytestosterone;7-hydroxytestosterone, (7beta,17beta)-isomer

Suppliers and Price of 7alpha,17beta-Dihydroxyandrost-4-en-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of 7alpha,17beta-Dihydroxyandrost-4-en-3-one

Chemical Property:

Vapor Pressure:3.84E-11mmHg at 25°C
Melting Point:218-220 °C
Boiling Point:478°C at 760 mmHg
PKA:14.40±0.70(Predicted)
Flash Point:257°C
PSA：57.53000
Density:1.19g/cm³
LogP:2.85000
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:304.20384475
Heavy Atom Count:22
Complexity:539

Purity/Quality:: 99.5% ^*data from raw suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 61-40
Safety Statements: 53-22-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2O)C(CC4=CC(=O)CCC34C)O
Uses 7α-Hydroxytestosterone, is a metabolite of Testosterone (T155000), a principal hormone of the testes, produced by the interstitial cells.

Technology Process of 7alpha,17beta-Dihydroxyandrost-4-en-3-one

There total 9 articles about 7alpha,17beta-Dihydroxyandrost-4-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 58-22-0
testosterone

: 12,15α-dihydroxymethyltestosterone

: 2226-70-2
15alpha-Hydroxytestosterone

: 62-83-9,969-13-1
7α,17β-dihydroxyandrost-4-en-3-one

Guidance literature:: With D-glucose; In water; at 25 ℃; for 120h;
DOI:10.1007/s10600-011-9830-7

Reference yield:

: 521-17-5,1963-03-7,4593-57-1,4593-58-2,14504-94-0,16895-59-3,47122-33-8,64162-67-0,75767-22-5,139973-51-6,151284-19-4
5-androstenediol

: 2487-48-1,7522-54-5,62357-03-3,53-00-9
3β,7α-dihydroxyandrost-5-ene-17-one

: 62-83-9,969-13-1
7α,17β-dihydroxyandrost-4-en-3-one

: 3β,14α,17β-trihydroxyandrost-5-en-7-one

: 3β,5β,6α,7α,17β-pentahydroxyandrostane

: 3β,5α,6β,7α,17β-pentahydroxyandrostane

: 3β,5α,6β,7β,17β-pentahydroxyandrostane

: 3β,5α,6β,11α,17β-pentahydroxyandrostane

: 3β,5α,6β,15β,17β-pentahydroxyandrostane

: 3β,5α,6β,14α,17β-pentahydroxyandrostane

: 2697-85-0,62357-04-4,2226-66-6
Androst-5-ene-3beta,7alpha,17beta-triol

: 2697-85-0
5-androstene-3β,7β,17β-triol

Guidance literature:: With water; In ethanol; for 120h; Microbiological reaction;
DOI:10.1016/j.molcatb.2015.11.026

Reference yield:

: 53-43-0
dehydroepiandrosterone

: 2487-48-1,7522-54-5,62357-03-3,53-00-9
3β,7α-dihydroxyandrost-5-ene-17-one

: 62-83-9,969-13-1
7α,17β-dihydroxyandrost-4-en-3-one

: 3β,14α,17β-trihydroxyandrost-5-en-7-one

: 3β,5β,6α,7α,17β-pentahydroxyandrostane

: 3β,5α,6β,7α,17β-pentahydroxyandrostane

: 3β,5α,6β,7β,17β-pentahydroxyandrostane

: 3β,5α,6β,11α,17β-pentahydroxyandrostane

: 3β,5α,6β,15β,17β-pentahydroxyandrostane

: 3β,5α,6β,14α,17β-pentahydroxyandrostane

: 2697-85-0,62357-04-4,2226-66-6
Androst-5-ene-3beta,7alpha,17beta-triol

: 2697-85-0
5-androstene-3β,7β,17β-triol

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol

2: water / ethanol / 120 h / Microbiological reaction

With sodium tetrahydroborate; water; In methanol; ethanol;
DOI:10.1016/j.molcatb.2015.11.026