4-(N-Methylaminomethyl)-1-oxo-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole oxalate

Base Information

Chemical Name:4-(N-Methylaminomethyl)-1-oxo-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole oxalate
CAS No.:73424-88-1
Molecular Formula:C₂H₂O₄*C₁₃H₁₆N₂OS
Molecular Weight:338.384
Hs Code.:
DSSTox Substance ID:DTXSID40994151

Synonyms:4-(N-Methylaminomethyl)-1-oxo-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole oxalate;73424-88-1;Thiopyrano(2,3-b)indole-4-methanamine, 2,3,4,9-tetrahydro-N-methyl-, 1-oxide, ethanedioate (1:1);DTXSID40994151;C13H16N2OS.C2H2O4;LS-153266;C13-H16-N2-O-S.C2-H2-O4;Oxalic acid--4-[(methylamino)methyl]-2,3,4,9-tetrahydro-1H-1lambda~4~-thiopyrano[2,3-b]indol-1-one (1/1)

Suppliers and Price of 4-(N-Methylaminomethyl)-1-oxo-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole oxalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(N-Methylaminomethyl)-1-oxo-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole oxalate

Chemical Property:

Vapor Pressure:1.24E-09mmHg at 25°C
Boiling Point:486.9°Cat760mmHg
Flash Point:248.3°C
Density:g/cm³
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:338.09364285
Heavy Atom Count:23
Complexity:381

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNCC1CCS(=O)C2=C1C3=CC=CC=C3N2.C(=O)(C(=O)O)O

Technology Process of 4-(N-Methylaminomethyl)-1-oxo-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole oxalate

There total 4 articles about 4-(N-Methylaminomethyl)-1-oxo-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59-48-3
2-oxoindole

: 73424-88-1
Methyl-(1-oxo-2,3,4,9-tetrahydro-1H-1λ⁴-thiopyrano[2,3-b]indol-4-ylmethyl)-amine; compound with oxalic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / P₂S₅, NaHCO₃ / tetrahydrofuran / 3 h / Ambient temperature

2: NaBH₄ / 1./ HOCH₂CCCHOH, K₂CO₃; 2./ CH₃NH₂, NaBH₄

3: 1) NaIO₄ / 1) MeOH, H₂O, 4 h, RT

With sodium tetrahydroborate; sodium periodate; tetraphosphorus decasulfide; sodium hydrogencarbonate; In tetrahydrofuran;
DOI:10.1248/cpb.32.877

Reference yield:

: 496-30-0
indolin-2-thione

: 73424-88-1
Methyl-(1-oxo-2,3,4,9-tetrahydro-1H-1λ⁴-thiopyrano[2,3-b]indol-4-ylmethyl)-amine; compound with oxalic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH₄ / 1./ HOCH₂CCCHOH, K₂CO₃; 2./ CH₃NH₂, NaBH₄

2: 1) NaIO₄ / 1) MeOH, H₂O, 4 h, RT

With sodium tetrahydroborate; sodium periodate;
DOI:10.1248/cpb.32.877