Methyl (11-beta)-((11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)sulfinyl)acetate

Base Information

Chemical Name:Methyl (11-beta)-((11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)sulfinyl)acetate
CAS No.:114967-90-7
Molecular Formula:C₂₄H₃₄O₇S
Molecular Weight:466.596
Hs Code.:

Synonyms:BRN 3575341;Methyl (11-beta)-((11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)sulfinyl)acetate;Acetic acid, ((11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)sulfinyl)-, methyl ester, (11-beta)-

Suppliers and Price of Methyl (11-beta)-((11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)sulfinyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl (11-beta)-((11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)sulfinyl)acetate

Chemical Property:

Vapor Pressure:5.58E-22mmHg at 25°C
Boiling Point:689.2°Cat760mmHg
Flash Point:370.6°C
Density:1.35g/cm³
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:6
Exact Mass:466.20252459
Heavy Atom Count:32
Complexity:897

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CS(=O)CC(=O)OC)O)C)O
Isomeric SMILES:C[C@]12CCC(=O)C=C1CCC3C2[C@H](C[C@]4(C3CC[C@@]4(C(=O)CS(=O)CC(=O)OC)O)C)O

Technology Process of Methyl (11-beta)-((11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)sulfinyl)acetate

There total 5 articles about Methyl (11-beta)-((11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)sulfinyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.4%

: 114967-89-4
(11β,17α-Dihydroxy-4-pregnene-3,20-dion-21-yl-21-thio)acetic acid methyl ester

: 114967-90-7
(11β,17α-Dihydroxy-4-pregnene-3,20-dion-21-yl-21-sulfenyl)acetic acid methyl ester

Guidance literature:: With periodic acid; In ethanol; water; at 0 - 5 ℃; for 18h; different reagents;

Reference yield:

: 63644-48-4
Cortisol 21-tosylate

: 114967-90-7
(11β,17α-Dihydroxy-4-pregnene-3,20-dion-21-yl-21-sulfenyl)acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaOMe / 1.) MeOH, 2.) acetone

2: 71.4 percent / periodic acid / ethanol; H₂O / 18 h / 0 - 5 °C / different reagents

With sodium methylate; periodic acid; In ethanol; water;

Reference yield:

: 33767-06-5
11β,17α-dihydroxy-21-iodopregn-4-ene-3,20-dione

: 114967-90-7
(11β,17α-Dihydroxy-4-pregnene-3,20-dion-21-yl-21-sulfenyl)acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaOMe / 1.) MeOH, 2.) acetone

2: 71.4 percent / periodic acid / ethanol; H₂O / 18 h / 0 - 5 °C / different reagents

With sodium methylate; periodic acid; In ethanol; water;