NCCH=C=O

Base Information

• Chemical Name: NCCH=C=O
• CAS No.: 4452-08-8
• Molecular Formula: C3H N O
• Molecular Weight: 67.047
• Hs Code.: 2926909090
• Mol file: 4452-08-8.mol

Synonyms:Acrylonitrile,3-oxo- (8CI); Cyanoketene; Ketene, cyano-

Chemical Property of NCCH=C=O

Chemical Property:

• Vapor Pressure: 54.7mmHg at 25°C
• Boiling Point: 91.1°Cat760mmHg
• Flash Point: 8.9°C
• PSA: 40.86000
• Density: 0.994g/cm³
• LogP: -0.10222

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NCCH=C=O

There total 18 articles about NCCH=C=O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

ethyl 2-cyanoacetate (105-56-6) → cyanoketene (4452-08-8) + 2,4,6-tricyano-3,5-dihydroxyphenyl dihydrogen phosphate

Guidance literature:

With phosphorus pentoxide; at 90 ℃; for 0.666667h;

Reference yield: 19.0%

ethyl 2-cyanoacetate (105-56-6) → cyanoketene (4452-08-8) + cyanoacetic dihydrogen phosphoric anhydride + 1,3,5-Trihydroxy-2,4,6-tricyanobenzene (137438-64-3) + 2,4,6-tricyanocyclohexane-1,3,5-trione

Guidance literature:

With pyrophosphoric acid; at 90 ℃; for 0.5h; Yield given. Further byproducts given. Title compound not separated from byproducts;

Reference yield: 19.0%

ethyl 2-cyanoacetate (105-56-6) → cyanoketene (4452-08-8) + cyanoacetic dihydrogen phosphoric anhydride + cyanoacetic trihydrogen pyrophosphoric anhydride + 2,4,6-tricyanobenzene-1,3,5-triyl tris(trihydrogen pyrophosphate)

Guidance literature:

With pyrophosphoric acid; at 90 ℃; for 0.5h; Further byproducts given;

upstream raw materials:

Cyanessigsaeure-o-nitrophenylester

ethyl 2-cyanoacetate

cyanoacetanilide

N-(4-chlorophenyl)-2-cyanoacetamide

Refernces

• 1、 Moloney, Daniel W. J.,Wong, Ming Wah,Flammang, Robert,Wentrup, Curt. "Cyanoketene and Iminopropadienones". . p. 4240 - 4247. Retrieved 2007/10/03.
• 2、 Al-Awadi,Elnagdi,Mathew,El-Gamry,Abdel Khalik. "Pyrolysis of amino nitriles, cyanohydrazones, and cyanoacetamides. Part I. Elimination reaction of 1-arylmethyleneamino-1,2-dihydro-4, 6-dimethyl-2-oxopyridine-3-carbonitriles and substituted benzaldehyde cyanoacetylhydrazones". . p. 741 - 748. Retrieved 2007/10/03.