2,6-Bis(4-bromophenyl)-3-phenylpiperidin-4-ol

Base Information

Chemical Name:2,6-Bis(4-bromophenyl)-3-phenylpiperidin-4-ol
CAS No.:124069-11-0
Molecular Formula:C23H21 Br2 N O
Molecular Weight:487.23
Hs Code.:
DSSTox Substance ID:DTXSID50924702
Mol file:124069-11-0.mol

Synonyms:2,6-bis(4-bromophenyl)-3-phenylpiperidin-4-ol;124069-11-0;BRN 3628289;2,6-Di(4-bromophenyl)-3-phenyl-4-piperidinol;4-Piperidinol, 2,6-bis(4-bromophenyl)-3-phenyl-;C23H21Br2NO;Oprea1_242704;C23-H21-Br2-N-O;DTXSID50924702;STK367583;AKOS005443804;LS-116851

Suppliers and Price of 2,6-Bis(4-bromophenyl)-3-phenylpiperidin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,6-Bis(4-bromophenyl)-3-phenylpiperidin-4-ol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:595.887°C at 760 mmHg
Flash Point:314.181°C
PSA：32.26000
Density:1.561g/cm³
LogP:6.46080
XLogP3:5.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:486.99694
Heavy Atom Count:27
Complexity:453

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(C(NC1C2=CC=C(C=C2)Br)C3=CC=C(C=C3)Br)C4=CC=CC=C4)O

Technology Process of 2,6-Bis(4-bromophenyl)-3-phenylpiperidin-4-ol

There total 3 articles about 2,6-Bis(4-bromophenyl)-3-phenylpiperidin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 124069-07-4
3-phenyl-2,6-di-(p-bromophenyl)-4-oxopiperidine

: 124069-11-0
3-phenyl-2,6-di-(p-bromophenyl)-4-hydroxypiperidine

Guidance literature:: With sodium tetrahydroborate; In ethanol; 1.) 20 deg C, 1 h, 2.) 50 deg C, 20 min;
DOI:10.1007/BF00758420

Reference yield:

: 1122-91-4
4-bromo-benzaldehyde

: 124069-11-0
3-phenyl-2,6-di-(p-bromophenyl)-4-hydroxypiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / ammonium acetate / acetic acid / 15 h / 20 °C

2: 80 percent / NaBH₄ / ethanol / 1.) 20 deg C, 1 h, 2.) 50 deg C, 20 min

With ammonium acetate; sodium tetrahydroborate; In ethanol; acetic acid;
DOI:10.1007/BF00758420

Reference yield:

: 103-79-7,136675-26-8
1-phenyl-acetone

: 124069-11-0
3-phenyl-2,6-di-(p-bromophenyl)-4-hydroxypiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / ammonium acetate / acetic acid / 15 h / 20 °C

2: 80 percent / NaBH₄ / ethanol / 1.) 20 deg C, 1 h, 2.) 50 deg C, 20 min

With ammonium acetate; sodium tetrahydroborate; In ethanol; acetic acid;
DOI:10.1007/BF00758420