3,3'-(Phenylmethylene)bis(2-methyl-1h-indole)

Base Information

• Chemical Name: 3,3'-(Phenylmethylene)bis(2-methyl-1h-indole)
• CAS No.: 17371-59-4
• Molecular Formula: C25H22 N2
• Molecular Weight: 350.463
• NSC Number: 135867
• DSSTox Substance ID: DTXSID90938424
• Nikkaji Number: J2.279.256C
• Wikidata: Q82914735
• Mol file: 17371-59-4.mol

Synonyms:17371-59-4;3,3'-(phenylmethylene)bis(2-methyl-1h-indole);NSC135867;3,3'-Benzylidenebis(2-methyl-1H-indole);DTXSID90938424;STK805526;AKOS000665198;NSC-135867;3,3'-(phenylmethanediyl)bis(2-methyl-1H-indole)

Chemical Property of 3,3'-(Phenylmethylene)bis(2-methyl-1h-indole)

Chemical Property:

• Boiling Point: 575°Cat760mmHg
• Flash Point: 256.5°C
• Density: 1.208g/cm³
• XLogP3: 6.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 350.178298710
• Heavy Atom Count: 27
• Complexity: 463

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C2=CC=CC=C2N1)C(C3=CC=CC=C3)C4=C(NC5=CC=CC=C54)C

Technology Process of 3,3'-(Phenylmethylene)bis(2-methyl-1h-indole)

There total 22 articles about 3,3'-(Phenylmethylene)bis(2-methyl-1h-indole) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-methyl-1H-indole (95-20-5) + benzaldehyde (100-52-7) → 2-methyl-3-((2-methyl-1H-indol-3-yl)(phenyl)methyl)-1H-indole (17371-59-4)

Guidance literature:

With C₆₂H₅₈N₈O₂₀Y₂Zn₂; In ethanol; water; for 2h;

DOI:10.1039/c6cc03608b

Reference yield: 98.0%

2-methyl-1H-indole (95-20-5) + benzyl alcohol (100-51-6,185532-71-2) → 2-methyl-3-((2-methyl-1H-indol-3-yl)(phenyl)methyl)-1H-indole (17371-59-4)

Guidance literature:

With palladium diacetate; sodium 3-(diphenylphosphanyl)benzenesulfonate; In water; at 60 ℃; for 16h; Sealed tube;

DOI:10.1039/c2ra21887a

Reference yield: 87.0%

2-methyl-1H-indole (95-20-5) + 1,3-diphenyl-2-(phenyl(2,4,6-trimethoxyphenyl)methyl)propane-1,3-dione → 2-methyl-3-((2-methyl-1H-indol-3-yl)(phenyl)methyl)-1H-indole (17371-59-4)

Guidance literature:

With iron(III) chloride; In acetonitrile; at 80 ℃; for 1h;

DOI:10.1039/c9nj00149b

upstream raw materials:

2-methyl-1H-indole

benzaldehyde

N-((2-methyl-1H-indol-3-yl)(phenyl)methyl)aniline

benzylidene phenylamine

Downstream raw materials:

(2R,3R)-(-)-2-methyl-3-benzylindoline