2,4-Difluoropyrimidine

Base Information

Chemical Name:2,4-Difluoropyrimidine
CAS No.:2802-61-1
Molecular Formula:C4H2F2N2
Molecular Weight:116.07
Hs Code.:29335990
European Community (EC) Number:631-074-8
NSC Number:331813
DSSTox Substance ID:DTXSID20182296
Nikkaji Number:J80.568H
Wikidata:Q83052955
Mol file:2802-61-1.mol

Synonyms:2,4-Difluoropyrimidine;2802-61-1;Pyrimidine, difluoro-;2,4-Difluoro-pyrimidine;Pyrimidine,2,4-difluoro-;Pyrimidine, 2,4-difluoro-;MFCD04972830;difluropyrimidine;NSC331813;SCHEMBL138862;2,4-Difluoropyrimidine, 97%;AMY136;DTXSID20182296;BCP07954;BBL100529;STL554323;AKOS005254452;NSC 331813;NSC-331813;SB57370;MS-20032;CS-0052149;FT-0677608;EN300-112151;2-(PHENYLTHIO)PYRIDINE-3-CARBONYLCHLORIDE;A819287;J-016950

Suppliers and Price of 2,4-Difluoropyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Difluoropyrimidine
100mg
$ 60.00

SynQuest Laboratories
2,4-Difluoropyrimidine 98%
10 g
$ 544.00

SynQuest Laboratories
2,4-Difluoropyrimidine 98%
5 g
$ 328.00

SynQuest Laboratories
2,4-Difluoropyrimidine 98%
1 g
$ 108.00

Sigma-Aldrich
2,4-Difluoropyrimidine 97%
500mg
$ 138.00

Sigma-Aldrich
2,4-Difluoropyrimidine 97%
100mg
$ 45.50

Matrix Scientific
2,4-Difluoropyrimidine 95%
1g
$ 52.00

Matrix Scientific
2,4-Difluoropyrimidine 95%
5g
$ 205.00

Biosynth Carbosynth
2,4-Difluoropyrimidine
10 g
$ 1050.00

Biosynth Carbosynth
2,4-Difluoropyrimidine
5 g
$ 550.00

Total 62 raw suppliers

Chemical Property of 2,4-Difluoropyrimidine

Chemical Property:

Vapor Pressure:2200mmHg at 25°C
Refractive Index:n20/D 1.432
Boiling Point:202.7 °C at 760 mmHg
PKA:-2.52±0.20(Predicted)
Flash Point:76.4 °C
PSA：25.78000
Density:1.376 g/cm³
LogP:0.75480
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:116.01860440
Heavy Atom Count:8
Complexity:78.4

Purity/Quality:

99% ^*data from raw suppliers

2,4-Difluoropyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi; Xn
Hazard Codes:Xn,Xi
Statements: 10-22-37/38-41
Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CN=C(N=C1F)F
Uses 2,4-Difluoropyrimidine can be used as a starting material to synthesize: 3-Pyrimidin-4-yl-oxazolidin-2-one derivatives as mutant isocitrate dehydrogenase (IDH1) inhibitors. N,N′-(1,4-phenylenebis(methylene))bis(2-fluoropyrimidin-4-amine) as chemokine receptor type 4 antagonists.

Technology Process of 2,4-Difluoropyrimidine

There total 3 articles about 2,4-Difluoropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%