3-Amino-4-ethyl-5H-pyrido(4,3-b)indole acetate

Base Information

Chemical Name:3-Amino-4-ethyl-5H-pyrido(4,3-b)indole acetate
CAS No.:75240-20-9
Molecular Formula:C₂H₄O₂*C₁₃H₁₃N₃
Molecular Weight:271.319
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20226225
Mol file:75240-20-9.mol

Synonyms:3-Amino-4-ethyl-5H-pyrido(4,3-b)indole acetate;75240-20-9;5H-Pyrido(4,3-b)indole, 3-amino-4-ethyl-, acetate;5H-Pyrido(4,3-b)indol-3-amine, 4-ethyl-, monoacetate;DTXSID20226225

Suppliers and Price of 3-Amino-4-ethyl-5H-pyrido(4,3-b)indole acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-Amino-4-ethyl-5H-pyrido(4,3-b)indole acetate

Chemical Property:

Vapor Pressure:4.28E-09mmHg at 25°C
Boiling Point:472.4°C at 760 mmHg
Flash Point:270.8°C
PSA：92.73000
LogP:2.88170
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:271.132076794
Heavy Atom Count:20
Complexity:287

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C2C(=CN=C1N)C3=CC=CC=C3N2.CC(=O)O

Technology Process of 3-Amino-4-ethyl-5H-pyrido(4,3-b)indole acetate

There total 5 articles about 3-Amino-4-ethyl-5H-pyrido(4,3-b)indole acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 64-19-7,77671-22-8
acetic acid

: 78788-96-2
2-(1-cyanopropyl)-3-formylindole

: 75240-20-9
4-Ethyl-5H-pyrido[4,3-b]indol-3-ylamine; compound with acetic acid

Guidance literature:: With ammonia; In methanol; Ambient temperature;
DOI:10.1248/cpb.29.1280

Reference yield:

: 52618-53-8
2-(cyanomethyl)-N-ethoxycarbonylindole

: 75240-20-9
4-Ethyl-5H-pyrido[4,3-b]indol-3-ylamine; compound with acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 55 percent / LDA / tetrahydrofuran / -78 °C

2: 90 percent / K₂CO₃ / methanol / Ambient temperature

3: 47 percent / phosphorous oxychloride / 1 h / Ambient temperature

4: 88 percent / NH₃ / methanol / Ambient temperature

With ammonia; potassium carbonate; lithium diisopropyl amide; trichlorophosphate; In tetrahydrofuran; methanol;
DOI:10.1248/cpb.29.1280

Reference yield:

: 17954-23-3
1-ethoxycarbonyl-1,2-dihydroquinoline-2-carbonitrile

: 75240-20-9
4-Ethyl-5H-pyrido[4,3-b]indol-3-ylamine; compound with acetic acid

Guidance literature:: Multi-step reaction with 5 steps

1: Irradiation

2: 55 percent / LDA / tetrahydrofuran / -78 °C

3: 90 percent / K₂CO₃ / methanol / Ambient temperature

4: 47 percent / phosphorous oxychloride / 1 h / Ambient temperature

5: 88 percent / NH₃ / methanol / Ambient temperature

With ammonia; potassium carbonate; lithium diisopropyl amide; trichlorophosphate; In tetrahydrofuran; methanol;
DOI:10.1248/cpb.29.1280