6-methyl-N-(2H-tetrazol-5-yl)pyridine-2-carboxamide

Base Information

Chemical Name:6-methyl-N-(2H-tetrazol-5-yl)pyridine-2-carboxamide
CAS No.:83282-08-0
Molecular Formula:C₈H₈N₆O
Molecular Weight:204.191
Hs Code.:
UNII:B4PERVZIM7
Nikkaji Number:J272.350F
ChEMBL ID:CHEMBL23549
Mol file:83282-08-0.mol

Synonyms:6-methyl-N-(2H-tetrazol-5-yl)pyridine-2-carboxamide;CHEMBL23549;TA-5707 FREE BASE;SCHEMBL8612811;PD160360;2-Pyridinecarboxamide, 6-methyl-N-1H-tetrazol-5-yl-;Z1097408339;6-METHYL-N-(1H-1,2,3,4-TETRAZOL-5-YL)PYRIDINE-2-CARBOXAMIDE

Suppliers and Price of 6-methyl-N-(2H-tetrazol-5-yl)pyridine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6-methyl-N-(2H-tetrazol-5-yl)pyridine-2-carboxamide

Chemical Property:

Melting Point:248 - 249 °C
Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：96.45000
Density:1.58g/cm³
LogP:0.22840
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:204.07595890
Heavy Atom Count:15
Complexity:235

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NC(=CC=C1)C(=O)NC2=NNN=N2

Technology Process of 6-methyl-N-(2H-tetrazol-5-yl)pyridine-2-carboxamide

There total 3 articles about 6-methyl-N-(2H-tetrazol-5-yl)pyridine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4418-61-5
5-aminotetrazole

: 126125-54-0
6-methyl-pyridine-2-carbonyl chloride

: 83282-08-0
6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 2h; Yield given;
DOI:10.1021/jm00368a005

Reference yield:

: 4418-61-5
5-aminotetrazole

: 934-60-1
6-methyl-2-pyridinecarboxylic acid

: 83282-08-0
6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide

Guidance literature:: With thionyl chloride;

Reference yield:

: 87884-49-9
6-methylpyridine-2-carboxylic acid hydrochlorid salt

: 83282-08-0
6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 2 h / Heating

2: Et₃N / dimethylformamide / 2 h / 80 °C

With thionyl chloride; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1021/jm00368a005