1,2,3-Triazolo(4,5-d)(2)benzazepine, 2,4-dihydro-8-chloro-6-(2-chlorophenyl)-

Base Information

Chemical Name:1,2,3-Triazolo(4,5-d)(2)benzazepine, 2,4-dihydro-8-chloro-6-(2-chlorophenyl)-
CAS No.:78131-55-2
Molecular Formula:C16H10Cl2N4
Molecular Weight:329.1834
Hs Code.:
DSSTox Substance ID:DTXSID80228785
ChEMBL ID:CHEMBL339776

Synonyms:BRN 6069093;1,2,3-Triazolo(4,5-d)(2)benzazepine, 2,4-dihydro-8-chloro-6-(2-chlorophenyl)-;2,4-Dihydro-8-chloro-6-(2-chlorophenyl)-1,2,3-triazolo(4,5-d)(2)benzazepine;8-Chloro-6-(2-chlorophenyl)-2H,4H-(1,2,3)triazolo(4,5-d)(2)benzazepine;78131-55-2;CHEMBL339776;SCHEMBL11109482;DTXSID80228785;LS-156274

Suppliers and Price of 1,2,3-Triazolo(4,5-d)(2)benzazepine, 2,4-dihydro-8-chloro-6-(2-chlorophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2,3-Triazolo(4,5-d)(2)benzazepine, 2,4-dihydro-8-chloro-6-(2-chlorophenyl)-

Chemical Property:

Vapor Pressure:7.02E-12mmHg at 25°C
Boiling Point:557.2°Cat760mmHg
Flash Point:290.8°C
Density:1.54g/cm³
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:328.0282517
Heavy Atom Count:22
Complexity:444

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=NNN=C2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4Cl

Technology Process of 1,2,3-Triazolo(4,5-d)(2)benzazepine, 2,4-dihydro-8-chloro-6-(2-chlorophenyl)-

There total 3 articles about 1,2,3-Triazolo(4,5-d)(2)benzazepine, 2,4-dihydro-8-chloro-6-(2-chlorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 83948-82-7
4-<4-chloro-2-(2-chlorobenzoyl)phenyl>-5-(N-phthalimidomethyl)-2H-1,2,3-triazole

: 78131-55-2
8-chloro-6-(2-chlorophenyl)-2H,4H-<1,2,3>triazolo<4,5-d><2>benzazepine

Guidance literature:: With methylamine; In ethanol; for 12h; Ambient temperature;
DOI:10.1021/jm00357a011

Reference yield:

: 76049-54-2
N-<<4-chloro-2-(2-chlorobenzoyl)phenyl>-3-propynyl>isoindole-1,3(2H)-dione

: 78131-55-2
8-chloro-6-(2-chlorophenyl)-2H,4H-<1,2,3>triazolo<4,5-d><2>benzazepine

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / sodium azide, acetic acid / dimethylsulfoxide / 48 h / 50 °C

2: 60 percent / 40 percent aq. methylamine / ethanol / 12 h / Ambient temperature

With sodium azide; acetic acid; methylamine; In ethanol; dimethyl sulfoxide;
DOI:10.1021/jm00357a011