76049-54-2

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[3-[4-chloro-2-(2-chlorobenzoyl)phenyl]-2-propynyl]-
• Synonyms: 1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-phthalimidopropyne;1-[4- chloro-2-(2-chlorobenzoyl)phenyl]-3-phthalimidopropyne
• CAS NO: 76049-54-2
• Molecular Formula: C24H13Cl2NO3
• Molecular Weight: 434.278
• Mol File: 76049-54-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 144-145 °C(Solv: acetone (67-64-1))
• Boiling Point: 633.7±55.0 °C(Predicted)
• Density: 1.49±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[3-[4-chloro-2-(2-chlorobenzoyl)phenyl]-2-propynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[3-[4-chloro-2-(2-chlorobenzoyl)phenyl]-2-propynyl]-(76049-54-2)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[3-[4-chloro-2-(2-chlorobenzoyl)phenyl]-2-propynyl]-(76049-54-2)

Safety Data

• Hazardous Substances Data: 76049-54-2(Hazardous Substances Data)

Upstream product

• 2958-36-3 (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone 
• 7223-50-9 N-propargylphthalimide 
• 76049-50-8 2',5-dichloro-2-iodobenzophenone 

Downstream Products

• 81389-26-6 8-chloro-1-(2-chlorophenyl)-3,5-dihydrospiro<4H-2-benzazepine-4,2'-<1,3>dithiolane> 
• 76049-70-2 8-chloro-1-(2-chlorophenyl)-3,4-dihydro-5H-2-benzazepin-5-one 
• 76049-71-3 methanesulfonate of 8-chloro-3,4-dihydro-1-(2-chlorophenyl)-5H-2-benzazepin-5-one 
• 81389-14-2 2-<<5-chloro-3-(2-chlorophenyl)-2,3-dihydro-3-hydroxy-1-oxo-1H-inden-2-yl>methyl>-1H-isoindole-1,3(2H)-dione 
• 81389-12-0 2-<1-<6-chloro-4-(2-chlorophenyl)-1-phthalazinyl>ethyl>-1H-isoindole-1,3(2H)-dione 
• 81389-13-1 2-<<5-chloro-3-(2-chlorophenyl)-1-oxo-1H-inden-2-yl>methyl>-1H-isoindole-1,3(2H)-dione 
• 81389-15-3 8-chloro-9b-(2-chlorophenyl)-3,4-dihydro-9aH-oxazirino<3,2-a><2>benzazepin-5-(5H)-one 
• 81389-23-3 8-chloro-1-(2-chlorophenyl)-4-(1-pyrrolidinyl)-3H-2-benzazepine 
• 76049-78-0 8-chloro-1-(2-chlorophenyl)-3,4-dihydro-5H-2-benzazepin-5-one 2-oxide 
• 81389-16-4 5-chloro-3-(2-chlorophenyl)-1,3-dihydro-3-hydroxyazirino<1,2-b>isoquinolin-8(8aH)-one 
• 101713-35-3 (2-chlorophenyl)<4-chloro-2-(3,3-dimethoxypropanyl)phenyl>methanone imine 
• 101713-37-5 8-chloro-1-(2-chlorophenyl)-4,5-dihydro-3H-2-benzazepin-3-ol acetate 
• 101713-36-4 8-chloro-1-(2-chlorophenyl)-4,5-dihydro-3H-2-benzazepine 2-oxide 
• 101713-34-2 8-chloro-1-(2-chlorophenyl)-4,5-dihydro-3-methoxy-3H-2-benzazepine 

Relevant articles and documents

3H-2-Benzazepines

There is presented 3H-2-benzazepines and 4,5-dihydro-3H-2-benzazepines of the formula STR1 wherein X is hydrogen, chloro or bromo, Y is hydrogen, fluoro or chloro with the proviso that X and Y cannot both be hydrogen and R1 is selected from the

N-oxides of 5-oxo-1-phenyl-2-benzazepines

Compounds of the formula STR1 wherein X and Y are selected from the group consisting of hydrogen, halogen and trifluoromethyl, are disclosed. The compounds are useful as intermediates in the production of 2-benzazepines, compounds of pharmacological activ

2-Benzazepines. 1. Synthesis of 2-Benzazepin-4-ones and -5-ones via 2-Acetylenic Benzophenones

The preparation of 1-phenyl-2-benzazepin-4-ones and -5-ones is discussed.The palladium-catalyzed coupling of an iodobenzophenone to a monosubstituted acetylene assembles the necessary atoms required for the benzazepine ring.Transformation of the acetylene