1-Hydroxy-2-methoxyanthraquinone

Base Information

Chemical Name:1-Hydroxy-2-methoxyanthraquinone
CAS No.:6003-11-8
Molecular Formula:C15H10 O4
Molecular Weight:254.242
Hs Code.:2914690090
DSSTox Substance ID:DTXSID30208759
Nikkaji Number:J81.128I
Wikidata:Q27105724
Metabolomics Workbench ID:67948
ChEMBL ID:CHEMBL451977
Mol file:6003-11-8.mol

Synonyms:1-Hydroxy-2-methoxyanthraquinone;Alizarin 2-methyl ether;6003-11-8;1-hydroxy-2-methoxyanthracene-9,10-dione;Anthraquinone, 1-hydroxy-2-methoxy-;CCRIS 6434;alizarin-2-methyl ether;CHEBI:2575;1-Hydroxy-2-methoxyanthra-9,10-quinone;Alizarin-2-methyl-ether;MLS001049042;CHEMBL451977;SCHEMBL1426486;DTXSID30208759;STL564978;AKOS030495513;NCGC00246219-01;SMR000387052;1-Hydroxy-2-methoxyanthra-9,10-quinone #;LS-188367;1-hydroxy-2-methoxy-anthracene-9,10-dione;9,10-Anthracenedione, 1-hydroxy-2-methoxy-;AE-848/01284025;SR-01000262737;SR-01000262737-1;Q27105724;1-HYDROXY-2-METHOXY-9,10-DIHYDROANTHRACENE-9,10-DIONE

Suppliers and Price of 1-Hydroxy-2-methoxyanthraquinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
Alizarin2-methylether
5mg
$ 418.00

American Custom Chemicals Corporation
1-HYDROXY-2-METHOXYANTHRAQUINONE 95.00%
5MG
$ 496.22

Total 7 raw suppliers

Chemical Property of 1-Hydroxy-2-methoxyanthraquinone

Chemical Property:

Vapor Pressure:2.78E-09mmHg at 25°C
Boiling Point:465.4°C at 760 mmHg
Flash Point:181.2°C
PSA：63.60000
Density:1.4g/cm³
LogP:2.17620
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:254.05790880
Heavy Atom Count:19
Complexity:392

Purity/Quality:

Analysis control,HPLC≥95% ^*data from raw suppliers

Alizarin2-methylether ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C2=C(C=C1)C(=O)C3=CC=CC=C3C2=O)O
General Description 1-Hydroxy-2-methoxyanthraquinone (also known as Alizarin 2-methyl ether) is an anthraquinone derivative that exhibits anti-inflammatory properties, as demonstrated by its ability to inhibit nitric oxide production in LPS-stimulated RAW264.7 macrophages. While it shows moderate inhibitory effects on 15-lipoxygenase activity, it is less potent compared to other anthraquinones like 3-hydroxy-2-hydroxymethyl anthraquinone and damnacanthol. 1-HYDROXY-2-METHOXYANTHRAQUINONE's photochemical behavior has also been studied, revealing its involvement in photochromic reactions, particularly in acyl migration processes in triplet states. However, its role in biological systems, such as inflammation modulation, suggests potential therapeutic applications, though further research is needed to explore its clinical relevance.

Technology Process of 1-Hydroxy-2-methoxyanthraquinone

There total 43 articles about 1-Hydroxy-2-methoxyanthraquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 72-48-0,84754-86-9
1,2-dihydroxy-9,10-anthracenedione

: 74-88-4
methyl iodide

: 6003-11-8
1-hydroxy-2-methoxyanthraquinone

Guidance literature:: With lithium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 24h;

Reference yield: 88.0%

: 129770-14-5
Diethyl-carbamic acid 2-methoxy-9,10-dioxo-9,10-dihydro-anthracen-1-yl ester

: 6003-11-8
1-hydroxy-2-methoxyanthraquinone

Guidance literature:: With oxygen; In toluene; Irradiation;
DOI:10.1021/jp962658y

Reference yield: 85.0%

: C₁₂H₁₅NO₄

: 27613-27-0
3-oxo-1,3-dihydroisobenzofuran-1-carbonitrile

: 6003-11-8
1-hydroxy-2-methoxyanthraquinone

Guidance literature:: 3-oxo-1,3-dihydroisobenzofuran-1-carbonitrile; With lithium tert-butoxide; In tetrahydrofuran; at -78 ℃; for 0.333333h; Inert atmosphere;

C₁₂H₁₅NO₄; In tetrahydrofuran; at -78 - 20 ℃; for 0.583333h; Inert atmosphere;
DOI:10.1002/anie.201507007