Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-chloro-

Base Information

Chemical Name:Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-chloro-
CAS No.:81257-94-5
Molecular Formula:C₁₁H₁₀ClNO
Molecular Weight:207.659
Hs Code.:
DSSTox Substance ID:DTXSID50230996
Wikidata:Q83111797
Mol file:81257-94-5.mol

Synonyms:81257-94-5;Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-chloro-;1,7,8,9-Tetrahydro-5-chloropyrano(2,3-g)indole;5-Chloro-7,8,9-trihydro-pyranno(2,3-g)indole [French];5-Chloro-7,8,9-trihydro-pyranno(2,3-g)indole;SCHEMBL10746598;DTXSID50230996;LS-127371

Suppliers and Price of Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-chloro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,7,8,9-TETRAHYDRO-5-CHLOROPYRANO(2,3-G)INDOLE 95.00%
5MG
$ 496.76

Total 3 raw suppliers

Chemical Property of Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-chloro-

Chemical Property:

Vapor Pressure:2.79E-06mmHg at 25°C
Boiling Point:401.2°C at 760 mmHg
Flash Point:196.4°C
PSA：25.02000
Density:1.368g/cm³
LogP:3.14630
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:207.0450916
Heavy Atom Count:14
Complexity:223

Purity/Quality:: 1,7,8,9-TETRAHYDRO-5-CHLOROPYRANO(2,3-G)INDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C3C(=CC(=C2OC1)Cl)C=CN3

Technology Process of Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-chloro-

There total 7 articles about Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 108-20-3
di-isopropyl ether

: 81257-91-2
acide chloro-5 tetrahydro-1,7,8,9-pyranno<2,3-g>indolecarboxylique-2

: 20562-62-3
pyrano[2,3-g]indole

: 81257-94-5
5-chloro-1,7,8,9-tetrahydropyrano<2,3-g>indole

Guidance literature:: copper chromite; In quinoline; hexane;

Reference yield: 74.0%

: 81257-91-2
acide chloro-5 tetrahydro-1,7,8,9-pyranno<2,3-g>indolecarboxylique-2

: 81257-94-5
5-chloro-1,7,8,9-tetrahydropyrano<2,3-g>indole

Guidance literature:: With chromium(III) oxide; copper(II) oxide; In quinoline; at 190 - 195 ℃; for 7.5h;
DOI:10.1139/v82-298

Reference yield:

: 81258-19-7
bromo-6 chloro-8 chromanne

: 81257-94-5
5-chloro-1,7,8,9-tetrahydropyrano<2,3-g>indole

Guidance literature:: Multi-step reaction with 5 steps

1: 1) n-butyllithium / 1) ether, -70 deg C, 6 h; 2) ether, -70 deg C, 12 h

2: Na / methanol / 6 h / 0 °C

3: 55.5 percent / N₂ / various solvent(s) / 0.33 h / 110 °C

4: 93 percent / 1) KOH, H₂O; 2) 5 N HCl / 1) reflux, 3.5 h; 2) 0 deg C

5: 74 percent / CuO, Cr₂O₃ / quinoline / 7.5 h / 190 - 195 °C

With hydrogenchloride; chromium(III) oxide; potassium hydroxide; n-butyllithium; nitrogen; water; sodium; copper(II) oxide; In quinoline; methanol;
DOI:10.1139/v82-298