3H-Pyrano(3,2-f)quinolin-3-one

Base Information

• Chemical Name: 3H-Pyrano(3,2-f)quinolin-3-one
• CAS No.: 4959-99-3
• Molecular Formula: C12H7NO2
• Molecular Weight: 197.1895
• NSC Number: 140712
• UNII: 9F1YT72QWB
• DSSTox Substance ID: DTXSID50197914
• Nikkaji Number: J2.769.096C
• Wikidata: Q83070678
• ChEMBL ID: CHEMBL1985459
• Mol file: 4959-99-3.mol

Synonyms:3H-Pyrano(3,2-f)quinolin-3-one;4959-99-3;3H-Pyrano[3,2-f]quinolin-3-one;NSC140712;9F1YT72QWB;MLS002920517;NSC-140712;pyrano[3,2-f]quinolin-3-one;3H-Pyrano[3,2-f]quinoline-3-one;NSC 140712;UNII-9F1YT72QWB;CHEMBL1985459;DTXSID50197914;SMR001798106;5-QUINOLINEACRYLIC ACID, 6-HYDROXY-, .DELTA.-LACTONE

Chemical Property of 3H-Pyrano(3,2-f)quinolin-3-one

Chemical Property:

• Vapor Pressure: 2.84E-07mmHg at 25°C
• Boiling Point: 420.3°Cat760mmHg
• Flash Point: 208°C
• Density: 1.365g/cm³
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 197.047678466
• Heavy Atom Count: 15
• Complexity: 300

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC2=C(C=CC3=C2C=CC(=O)O3)N=C1

Technology Process of 3H-Pyrano(3,2-f)quinolin-3-one

There total 12 articles about 3H-Pyrano(3,2-f)quinolin-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

6-(prop-2-ynylamino)-2H-chromone-2-one (1286272-48-7) → 3H-pyrano[3,2-f]quinoline-3-one (4959-99-3)

Guidance literature:

With silver hexafluoroantimonate; In dimethyl sulfoxide; at 110 ℃; for 0.75h; regioselective reaction;

DOI:10.1055/s-0030-1259097

Reference yield:

C12H11NO → 3H-pyrano[3,2-f]quinoline-3-one (4959-99-3)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1039/b912887e

Reference yield:

6-aminocoumarin (14415-44-2) → 3H-pyrano[3,2-f]quinoline-3-one (4959-99-3)

Guidance literature:

With arsenic(V) oxide; sulfuric acid; glycerol;

upstream raw materials:

6-hydroxyquinoline

malic acid

6-aminocoumarin

glycerol