1-Acridinol, 1,2,3,4-tetrahydro-6-chloro-9-((phenylmethyl)amino)-

Base Information

Chemical Name:1-Acridinol, 1,2,3,4-tetrahydro-6-chloro-9-((phenylmethyl)amino)-
CAS No.:104628-21-9
Molecular Formula:C₂₀H₁₉ClN₂O
Molecular Weight:338.837
Hs Code.:
DSSTox Substance ID:DTXSID40909068
ChEMBL ID:CHEMBL51063
Mol file:104628-21-9.mol

Synonyms:104628-21-9;1-Acridinol, 1,2,3,4-tetrahydro-6-chloro-9-((phenylmethyl)amino)-;9-(benzylamino)-6-chloro-1,2,3,4-tetrahydroacridin-1-ol;6-Chloro-9-((phenylmethyl)amino)-1,2,3,4-tetrahydro-1-acridinol;CHEMBL51063;BDBM9380;SCHEMBL9874134;DTXSID40909068;LS-14557;9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1hh;9-Benzylamino-6-chloro-1,2,3,4-tetrahydroacridin-1-ol;9-(Benzylimino)-6-chloro-1,2,3,4,9,10-hexahydroacridin-1-ol

Suppliers and Price of 1-Acridinol, 1,2,3,4-tetrahydro-6-chloro-9-((phenylmethyl)amino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-Acridinol, 1,2,3,4-tetrahydro-6-chloro-9-((phenylmethyl)amino)-

Chemical Property:

Vapor Pressure:1.7E-12mmHg at 25°C
Boiling Point:540°Cat760mmHg
Flash Point:280.4°C
PSA：48.38000
Density:1.34g/cm³
LogP:4.29190
XLogP3:4.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:338.1185909
Heavy Atom Count:24
Complexity:414

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C2=C(C3=C(C=C(C=C3)Cl)N=C2C1)NCC4=CC=CC=C4)O

Technology Process of 1-Acridinol, 1,2,3,4-tetrahydro-6-chloro-9-((phenylmethyl)amino)-

There total 7 articles about 1-Acridinol, 1,2,3,4-tetrahydro-6-chloro-9-((phenylmethyl)amino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 104586-68-7
9-Benzylamino-6-chloro-3,4-dihydroacridin-1(2H)-one

: 104628-21-9
9-Benzylamino-6-chloro-1,2,3,4-tetrahydroacridin-1-ol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 2h;
DOI:10.1021/jm00128a024

Reference yield:

: 38487-86-4
2-amino-4-chlorobenzonitrile

: 104628-21-9
9-Benzylamino-6-chloro-1,2,3,4-tetrahydroacridin-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1: 96 percent / p-toluenesulfonic acid monohydrate / toluene / 2 h / Heating

2: 47 percent / K₂CO₃ / CuCl / tetrahydrofuran / 5 h / Heating

3: 50 percent / NaOH / 4N>4> / CH₂Cl₂; H₂O / 4 h

4: 73 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 2 h

With sodium hydroxide; lithium aluminium tetrahydride; potassium carbonate; toluene-4-sulfonic acid; tetra(n-butyl)ammonium hydrogensulfate; copper(l) chloride; In tetrahydrofuran; diethyl ether; dichloromethane; water; toluene;
DOI:10.1021/jm00128a024

Reference yield:

: 100-39-0
benzyl bromide

: 104628-21-9
9-Benzylamino-6-chloro-1,2,3,4-tetrahydroacridin-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / NaOH / 4N>4> / CH₂Cl₂; H₂O / 4 h

2: 73 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 2 h

With sodium hydroxide; lithium aluminium tetrahydride; tetra(n-butyl)ammonium hydrogensulfate; In tetrahydrofuran; diethyl ether; dichloromethane; water;
DOI:10.1021/jm00128a024