4-fluoro-N-(furan-2-ylmethyl)benzenesulfonamide

Base Information

• Chemical Name: 4-fluoro-N-(furan-2-ylmethyl)benzenesulfonamide
• CAS No.: 6341-35-1
• Molecular Formula: C11H10FNO3S
• Molecular Weight: 255.2654
• Hs Code.: 2935009090
• NSC Number: 46209
• DSSTox Substance ID: DTXSID90286497
• Wikidata: Q82022247
• Mol file: 6341-35-1.mol

Synonyms:6341-35-1;4-fluoro-N-(furan-2-ylmethyl)benzenesulfonamide;N-(FURAN-2-YLMETHYL) 4-FLUOROBENZENESULFONAMIDE;4-Fluoro-N-[(furan-2-yl)methyl]benzene-1-sulfonamide;4-fluoro-n-(2-furylmethyl)benzenesulfonamide;NSC46209;DTXSID90286497;MFCD01077680;NSC-46209;STK155923;AKOS000565714;SB61347;WAY-231670;BS-23681;CS-0208385;EU-0069868;EN300-15733;A868151;AG-690/12765520;SR-01000418020;SR-01000418020-1;Z45497831

Chemical Property of 4-fluoro-N-(furan-2-ylmethyl)benzenesulfonamide

Chemical Property:

• Vapor Pressure: 4.18E-06mmHg at 25°C
• Boiling Point: 384.2°Cat760mmHg
• Flash Point: 186.1°C
• PSA: 67.69000
• Density: 1.359g/cm³
• LogP: 3.36890
• Storage Temp.: 2-8°C
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 255.03654252
• Heavy Atom Count: 17
• Complexity: 333

Purity/Quality:

97% ^*data from raw suppliers

N-(Furan-2-ylmethyl)4-fluorobenzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)CNS(=O)(=O)C2=CC=C(C=C2)F

Technology Process of 4-fluoro-N-(furan-2-ylmethyl)benzenesulfonamide

There total 1 articles about 4-fluoro-N-(furan-2-ylmethyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

furan-2-ylmethanamine (617-89-0) + 4-Fluorobenzenesulfonyl chloride (349-88-2) → 4-fluoro-N-(furan-2-ylmethyl)benzenesulfonamide (6341-35-1)

Guidance literature:

In dichloromethane; for 2h;

DOI:10.1021/jo4011798

Reference yield: 93.0%

2-bromo-N-(tert-butyl)cyclopropanecarboxamide (1158733-15-3) + 4-fluoro-N-(furan-2-ylmethyl)benzenesulfonamide (6341-35-1) → N-(tert-butyl)-2-(4-fluoro-N-(furan-2-ylmethyl)phenylsulfonamido)cyclopropanecarboxamide

Guidance literature:

With 18-crown-6 ether; potassium hydroxide; In tetrahydrofuran; at 85 ℃; for 12h; diastereoselective reaction;

DOI:10.1021/jo4011798

upstream raw materials:

furan-2-ylmethanamine

4-Fluorobenzenesulfonyl chloride