(+)-Vincadifformine

Base Information

Chemical Name:(+)-Vincadifformine
CAS No.:18374-17-9
Molecular Formula:C₂₁H₂₆N₂O₂
Molecular Weight:338.45
Hs Code.:
DSSTox Substance ID:DTXSID201154585
Nikkaji Number:J953.532B
Mol file:18374-17-9.mol

Synonyms:(+)-Vincadifformine;Methyl 2,3-didehydroaspidospermidine-3-carboxylate;CHEBI:142834;DTXSID201154585;AKOS032949626;2,3-didehydroaspidospermidine-3-carboxylic acid methyl ester;aspidospermidine-3-carboxylic acid, 2,3-didehydro-, methyl ester;methyl (5R,12S,19R)-2,3-didehydroaspidospermidine-3-carboxylate;Aspidospermidine-3-carboxylic acid, 2,3-didehydro-, methyl ester, (+/-)-;methyl (1S,12R,19R)-12-ethyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9-tetraene-10-carboxylate

Suppliers and Price of (+)-Vincadifformine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (+)-Vincadifformine

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:338.199428076
Heavy Atom Count:25
Complexity:629

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12CCCN3C1C4(CC3)C5=CC=CC=C5NC4=C(C2)C(=O)OC
Isomeric SMILES:CC[C@]12CCCN3[C@H]1[C@]4(CC3)C5=CC=CC=C5NC4=C(C2)C(=O)OC

Technology Process of (+)-Vincadifformine

There total 151 articles about (+)-Vincadifformine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: methyl (+/-)-(3aR*,4S*,11bR*)-3-(2-bromoallyl)-2,3,3a,4,5,7-hexahydro-4-ethyl-4-(phenylselenyl)-1H-pyrrolo[2,3-d]carbazole-6-carboxylate

: 18374-17-9
(±)-vincadifformine

Guidance literature:: methyl (+/-)-(3aR*,4S*,11bR*)-3-(2-bromoallyl)-2,3,3a,4,5,7-hexahydro-4-ethyl-4-(phenylselenyl)-1H-pyrrolo[2,3-d]carbazole-6-carboxylate; With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 85 ℃; for 2h;

With triethylamine; In benzene; at 85 ℃; for 1h;
DOI:10.1021/jo960607r

Reference yield: 84.0%

: C₂₃H₃₀N₂O₃

: 18374-17-9
(±)-vincadifformine

Guidance literature:: With hydrogenchloride; In methanol; water; at 20 ℃; for 0.333333h; Inert atmosphere;
DOI:10.1002/anie.201605503

Reference yield: 81.2%

: 62498-23-1
5-chloro-2-ethylpentanal

: 75837-23-9
methyl 1-methyl-1,2,3,4-tetrahydro-9H-pyrido<3,4-b>indole-1-carboxylate

: 18374-17-9
(±)-vincadifformine

Guidance literature:: 5-chloro-2-ethylpentanal; methyl 1-methyl-1,2,3,4-tetrahydro-9H-pyrido<3,4-b>indole-1-carboxylate; With toluene-4-sulfonic acid; In toluene; for 100h; Heating;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; for 18h; Heating;
DOI:10.3390/61000803