(2-Aminoethyl)naphthalimide

Base Information

• Chemical Name: (2-Aminoethyl)naphthalimide
• CAS No.: 162265-51-2
• Molecular Formula: C14H12 N2 O2
• Molecular Weight: 240.261
• Nikkaji Number: J2.025.744J
• ChEMBL ID: CHEMBL42904
• Mol file: 162265-51-2.mol

Synonyms:(2-Aminoethyl)naphthalimide;162265-51-2;2-(2-Aminoethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione;N-(2-aminoethyl)-1,8-naphthalimide;CHEMBL42904;2-(2-aminoethyl)benzo[de]isoquinoline-1,3-dione;SCHEMBL626424;SCHEMBL5397805;SEWZPYPLFLUCCE-UHFFFAOYSA-N;CS-M3072;BDBM50491618;CS-13644;N-(2-Aminoethyl)naphthalene-1,8-dicarbimide;1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-(2-aminoethyl)-;2-(1,3-dioxo-1h, 3h-benzo[de]isoquinolin-2-yl)-ethylamine

Chemical Property of (2-Aminoethyl)naphthalimide

Chemical Property:

• PSA: 65.09000
• LogP: 1.61170
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 240.089877630
• Heavy Atom Count: 18
• Complexity: 339

Purity/Quality:

NLT 98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCN

Technology Process of (2-Aminoethyl)naphthalimide

There total 11 articles about (2-Aminoethyl)naphthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,8-Naphthalic anhydride (81-84-5) + ethylenediamine (107-15-3,85404-18-8) → N-(2-aminoethyl)-1,8-naphthalimide (162265-51-2)

Guidance literature:

In ethanol; Reflux;

DOI:10.1039/C9OB00406H

Reference yield: 76.0%

→ N-(2-aminoethyl)-1,8-naphthalimide (162265-51-2)

Guidance literature:

Reference yield: 70.0%

[2-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-ethyl]-carbamic acid tert-butyl ester (625123-44-6) → N-(2-aminoethyl)-1,8-naphthalimide (162265-51-2)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 8h;

DOI:10.1016/S0960-894X(03)00718-2

upstream raw materials:

1,8-Naphthalic anhydride

ethylenediamine

2-(2-phthalimido-ethyl)-benz[de]isoquinoline-1,3-dione

[2-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-ethyl]-carbamic acid tert-butyl ester

Downstream raw materials:

2-(2-((2-((2,4-dimethoxyphenyl)amino)ethyl)amino)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione