Benzo(b)thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-6-methyl-2-((1-piperidinylacetyl)amino)-, ethyl ester

Base Information

Chemical Name:Benzo(b)thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-6-methyl-2-((1-piperidinylacetyl)amino)-, ethyl ester
CAS No.:76981-90-3
Molecular Formula:C19H28N2O3S
Molecular Weight:364.5022
Hs Code.:
DSSTox Substance ID:DTXSID70998268

Synonyms:BRN 5610859;76981-90-3;Benzo(b)thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-6-methyl-2-((1-piperidinylacetyl)amino)-, ethyl ester;DTXSID70998268;LS-41190;Ethenyl 2-{[1-hydroxy-1-(piperidin-1-yl)ethyl]amino}-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

Suppliers and Price of Benzo(b)thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-6-methyl-2-((1-piperidinylacetyl)amino)-, ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzo(b)thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-6-methyl-2-((1-piperidinylacetyl)amino)-, ethyl ester

Chemical Property:

Vapor Pressure:2.41E-13mmHg at 25°C
Boiling Point:559.3°Cat760mmHg
Flash Point:292°C
Density:1.223g/cm³
XLogP3:5.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:364.18206393
Heavy Atom Count:25
Complexity:497

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC2=C(C1)SC(=C2C(=O)OC=C)NC(C)(N3CCCCC3)O

Technology Process of Benzo(b)thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-6-methyl-2-((1-piperidinylacetyl)amino)-, ethyl ester

There total 4 articles about Benzo(b)thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-6-methyl-2-((1-piperidinylacetyl)amino)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 110-89-4
piperidine

: 76981-87-8
2-(2-Chloro-acetylamino)-6-methyl-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester

: 76981-90-3
6-Methyl-2-(2-piperidin-1-yl-acetylamino)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester

Guidance literature:: for 1.5h; Heating;

Reference yield:

: 589-92-4
1-methylcyclohexan-4-one

: 76981-90-3
6-Methyl-2-(2-piperidin-1-yl-acetylamino)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / sulphur, diethylamine / ethanol / 1.5 h

2: 89 percent

3: 61 percent / 1.5 h / Heating

With sulfur; diethylamine; In ethanol;

Reference yield:

: 105-56-6
ethyl 2-cyanoacetate

: 76981-90-3
6-Methyl-2-(2-piperidin-1-yl-acetylamino)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / sulphur, diethylamine / ethanol / 1.5 h

2: 89 percent

3: 61 percent / 1.5 h / Heating

With sulfur; diethylamine; In ethanol;