N-Dodecanoylalanyl-N-(5,6-diamino-1-carboxy-6-oxohexyl)glutamine

Base Information

Chemical Name:N-Dodecanoylalanyl-N-(5,6-diamino-1-carboxy-6-oxohexyl)glutamine
CAS No.:78088-46-7
Molecular Formula:C₂₇H₄₉N₅O₈
Molecular Weight:571.715
Hs Code.:
DSSTox Substance ID:DTXSID20868462
Mol file:78088-46-7.mol

Synonyms:DTXSID20868462;N-Dodecanoylalanyl-N-(5,6-diamino-1-carboxy-6-oxohexyl)glutamine

Suppliers and Price of N-Dodecanoylalanyl-N-(5,6-diamino-1-carboxy-6-oxohexyl)glutamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TABILAUTIDE 95.00%
5MG
$ 504.90

Total 3 raw suppliers

Chemical Property of N-Dodecanoylalanyl-N-(5,6-diamino-1-carboxy-6-oxohexyl)glutamine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:943.4°C at 760 mmHg
Flash Point:524.3°C
PSA：231.01000
Density:1.173g/cm³
LogP:3.88720
XLogP3:0.1
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:24
Exact Mass:571.35811354
Heavy Atom Count:40
Complexity:823

Purity/Quality:

98% ^*data from raw suppliers

TABILAUTIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCC(=O)NC(C)C(=O)NC(CCC(=O)NC(CCCC(C(=O)N)N)C(=O)O)C(=O)O

Technology Process of N-Dodecanoylalanyl-N-(5,6-diamino-1-carboxy-6-oxohexyl)glutamine

There total 19 articles about N-Dodecanoylalanyl-N-(5,6-diamino-1-carboxy-6-oxohexyl)glutamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 78057-80-4,78148-13-7,78513-41-4
N²-1-benzyl-N-(N-lauroyl-L-alanyl)-γ-D-glutamyl>-N⁶-benzyloxycarbonyl-L-2,6-diaminopimelamic acid

: 78057-77-9,78088-46-7,78513-43-6
RP 56142

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; for 12h;

Reference yield:

: 41980-31-8
2,6-dicyanopiperidine

: 78057-77-9,78088-46-7,78513-43-6
RP 56142

Guidance literature:: Multi-step reaction with 13 steps

1: 98 percent / ammonium bicarbonate, NH₄OH / 4 h / 100 - 105 °C / autoclave

2: 70 percent / aq. HBr(48percent, d = 1.49) / 36 h / Heating

4: 1.) aq. NaOH, AcOH (pH 5.2), 2.) papain, L-cysteine, KH₂PO₄, Na₂HPO₄ / 2.) water, 24 h, 37 deg C

5: 91 percent / aq. HCl (d = 1.19), AcOH / 24 h / Heating

6: 1.) aq. NaOH (pH 8-9), dicyclohexylamine, 2.) aq. methanesulfonic acid / 1.) 0 deg C --> room temperature, 20 h, 2.) water, EtOAc

7: 89 percent / toluene-p-sulphonic acid / toluene / 5 h / Heating

8: 32 percent / KOH / phenylmethanol / 1.) 40 deg C, 7.5 h, 2.) 20 deg C, 16 h

9: 95 percent / NH₃ / methanol / 144 h / 20 °C / autoclave

10: 99 percent / aq. HCl (d = 1.19), H₂ / palladium-charcoal (3percent) / methanol / 4 h

11: 1.) CuBr₂, aq. NaOH (pH 10 --> 8), 2.) aq. HCl, H₂S (gas) / 1.) water, 20 deg C, 20 h, 2.) MeOH, 22 h

12: 1.) isobutyl chloroformate, Et₃N, 2.) NaOH / 1.) THF, -6 deg C, 20 min, 2.) water, 0 - 20 deg C, 17 h

13: 78 percent / H₂, AcOH / palladium-charcoal (10percent) / 12 h

With hydrogenchloride; potassium hydroxide; ammonium hydroxide; sodium hydroxide; disodium hydrogenphosphate; potassium dihydrogenphosphate; methanesulfonic acid; L-Cysteine; hydrogen sulfide; ammonia; hydrogen bromide; hydrogen; ammonium bicarbonate; toluene-4-sulfonic acid; acetic acid; triethylamine; N-cyclohexyl-cyclohexanamine; copper(ll) bromide; papain; isobutyl chloroformate; palladium on activated charcoal; In methanol; toluene; benzyl alcohol;

Reference yield:

: 41980-32-9
5,5'-trimethylenedihydantoin

: 78057-77-9,78088-46-7,78513-43-6
RP 56142

Guidance literature:: Multi-step reaction with 12 steps

1: 70 percent / aq. HBr(48percent, d = 1.49) / 36 h / Heating

3: 1.) aq. NaOH, AcOH (pH 5.2), 2.) papain, L-cysteine, KH₂PO₄, Na₂HPO₄ / 2.) water, 24 h, 37 deg C

4: 91 percent / aq. HCl (d = 1.19), AcOH / 24 h / Heating

5: 1.) aq. NaOH (pH 8-9), dicyclohexylamine, 2.) aq. methanesulfonic acid / 1.) 0 deg C --> room temperature, 20 h, 2.) water, EtOAc

6: 89 percent / toluene-p-sulphonic acid / toluene / 5 h / Heating

7: 32 percent / KOH / phenylmethanol / 1.) 40 deg C, 7.5 h, 2.) 20 deg C, 16 h

8: 95 percent / NH₃ / methanol / 144 h / 20 °C / autoclave

9: 99 percent / aq. HCl (d = 1.19), H₂ / palladium-charcoal (3percent) / methanol / 4 h

10: 1.) CuBr₂, aq. NaOH (pH 10 --> 8), 2.) aq. HCl, H₂S (gas) / 1.) water, 20 deg C, 20 h, 2.) MeOH, 22 h

11: 1.) isobutyl chloroformate, Et₃N, 2.) NaOH / 1.) THF, -6 deg C, 20 min, 2.) water, 0 - 20 deg C, 17 h

12: 78 percent / H₂, AcOH / palladium-charcoal (10percent) / 12 h

With hydrogenchloride; potassium hydroxide; sodium hydroxide; disodium hydrogenphosphate; potassium dihydrogenphosphate; methanesulfonic acid; L-Cysteine; hydrogen sulfide; ammonia; hydrogen bromide; hydrogen; toluene-4-sulfonic acid; acetic acid; triethylamine; N-cyclohexyl-cyclohexanamine; copper(ll) bromide; papain; isobutyl chloroformate; palladium on activated charcoal; In methanol; toluene; benzyl alcohol;