PIPERIDINE-2,6-DICARBONITRILE

Base Information

• Chemical Name: PIPERIDINE-2,6-DICARBONITRILE
• CAS No.: 41980-31-8
• Molecular Formula: C7H9 N3
• Molecular Weight: 135.169
• Hs Code.: 2933399090
• Mol file: 41980-31-8.mol

Synonyms:2,6-Dicyanopiperidine;NSC 337811

Chemical Property of PIPERIDINE-2,6-DICARBONITRILE

Chemical Property:

• Vapor Pressure: 6.73E-05mmHg at 25°C
• Boiling Point: 344.1°Cat760mmHg
• PKA: 2.84±0.10(Predicted)
• Flash Point: 161.9°C
• PSA: 59.61000
• Density: 1.1g/cm³
• LogP: 0.87306

Purity/Quality:

99% ^*data from raw suppliers

Piperidine-2,6-dicarbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of PIPERIDINE-2,6-DICARBONITRILE

There total 4 articles about PIPERIDINE-2,6-DICARBONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hydrogen cyanide (74-90-8) + Glutaraldehyde (111-30-8,29257-65-6,79215-57-9) → 2,6-dicyanopiperidine (41980-31-8)

Guidance literature:

With ammonia; In water; at 5 - 10 ℃; for 12h;

Reference yield:

N-nitroso-2,6-dicyanopiperidine (22905-25-5) → 2,6-dicyanopiperidine (41980-31-8)

Guidance literature:

With perchloric acid; ammonium sulfamate; sodium thiocyanide; at 50 ℃; Rate constant;

DOI:10.1021/jo01312a022

Reference yield:

sodium cyanide (143-33-9,25596-52-5) + Glutaraldehyde (111-30-8,29257-65-6,79215-57-9) → 2,6-dicyanopiperidine (41980-31-8)

Guidance literature:

With water; ammonium chloride;

DOI:10.1021/jo01091a620

upstream raw materials:

sodium cyanide

Glutaraldehyde

N-nitroso-2,6-dicyanopiperidine

hydrogen cyanide

Downstream raw materials:

N-nitroso-2,6-dicyanopiperidine

piperidine-2,6-dicarboxamide

6-carbamoyl-piperidine-2-carboxylic acid methyl ester

5,5'-trimethylenedihydantoin

Refernces

• 1、 -. "Processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof". . . Retrieved 2008/06/13.
• 2、 Roy,Karel. "An improved method for the preparation of isomeric , -diaminopimelic acid from glutaraldehyde.". . p. 942 - 943. Retrieved 2007/10/04.