2-Hydrazino-1H-benzimidazole

Base Information

• Chemical Name: 2-Hydrazino-1H-benzimidazole
• CAS No.: 15108-18-6
• Molecular Formula: C7H8N4
• Molecular Weight: 148.167
• Hs Code.: 2933990090
• European Community (EC) Number: 807-912-5
• NSC Number: 35802
• DSSTox Substance ID: DTXSID70164704
• Nikkaji Number: J1.152.591A
• Wikidata: Q72482791
• Mol file: 15108-18-6.mol

Synonyms:15108-18-6;2-Hydrazinyl-1H-benzo[d]imidazole;2-Hydrazino-1H-benzimidazole;2-Hydrazino-1H-1,3-benzimidazole;1H-benzimidazol-2-ylhydrazine;2-Hydrazinobenzimidazole;(1H-Benzoimidazol-2-yl)-hydrazine;2H-Benzimidazol-2-one, 1,3-dihydro-, hydrazone;2-Hydrazinyl-1H-1,3-Benzodiazole;MFCD00513603;1H-Benzimidazole,2-hydrazinyl-;(1H-Benzimidazol-2-yl)hydrazine;NSC35802;NSC 35802;2-Benzimidazolylhydrazine;Benzimidazole, 2-hydrazino-;Oprea1_261331;Oprea1_869688;2-hydrazino1-H-benzimidazole;2-hydrazinyl-1H-benzimidazole;SCHEMBL1800355;1H-Benzimidazole, 2-hydrazino-;1H-Benzimidazole, 2-hydrazinyl-;DTXSID70164704;AMY31418;NSC-35802;STK394300;AKOS000116228;AKOS028112899;s12070;SY081496;BB 0219178;CS-0067986;FT-0678894;EN300-03610;2-Hydrazono-2,3-dihydro-1H-benzo[d]imidazole;3Y-0941;A920789;J-509575;Z57087494;F0896-0068

Chemical Property of 2-Hydrazino-1H-benzimidazole

Chemical Property:

• Vapor Pressure: 4.77E-06mmHg at 25°C
• Melting Point: 224-225 °C
• Refractive Index: 1.841
• Boiling Point: 382.3°C at 760 mmHg
• PKA: 6.07±0.20(Predicted)
• Flash Point: 185°C
• PSA: 66.73000
• Density: 1.456g/cm³
• LogP: 1.62180
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 148.074896272
• Heavy Atom Count: 11
• Complexity: 138

Purity/Quality:

97% ^*data from raw suppliers

2-Hydrazino-1H-benzimidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)NC(=N2)NN

Technology Process of 2-Hydrazino-1H-benzimidazole

There total 10 articles about 2-Hydrazino-1H-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-bromo-1H-1,3-benzodiazole (54624-57-6) → 2-hydrazinobenzimidazole (15108-18-6)

Guidance literature:

With hydrazine hydrate; Reflux;

DOI:10.1016/j.molstruc.2016.12.044

Reference yield: 84.0%

1H-benzimidazole-2-sulfonic acid (40828-54-4) → 2-hydrazinobenzimidazole (15108-18-6)

Guidance literature:

With hydrazine hydrate; at 120 ℃; for 4h;

DOI:10.1021/acscombsci.9b00135

Reference yield: 84.0%

2-chloro-1H-benzoimidazole (4857-06-1) → 2-hydrazinobenzimidazole (15108-18-6)

Guidance literature:

With hydrazine hydrate; at 160 ℃; for 12h;

DOI:10.1021/jm300146f

upstream raw materials:

1H-benzimidazole-2-sulfonic acid

Benzimidazol-2-thiol

2-chloro-1H-benzoimidazole

1H-benzimidazol-2-ol

Downstream raw materials:

s-Triazolo<4,3-a>benzimidazol-3-thion

2-azido-1H-benzo[d]imidazole

9H-benzo[4,5]imidazo[1,2-d]tetrazole

1-{6-[[(1H-benzoimidazol-2-yl)-hydrazono]-(4-nitro-phenyl)-methyl]-benzo[1,3]dioxol-5-yl}-propan-2-ol