Formamidine hydrochloride

Base Information

• Chemical Name: Formamidine hydrochloride
• CAS No.: 6313-33-3
• Molecular Formula: CH5ClN2
• Molecular Weight: 80.5171
• Hs Code.: 29252900
• European Community (EC) Number: 228-639-2
• NSC Number: 39860
• UNII: PFC3YH7YHK
• Mol file: 6313-33-3.mol

Synonyms:formamidine;formamidine acetate;formamidine hydrochloride;formamidinium;methanimidamide

Chemical Property of Formamidine hydrochloride

Chemical Property:

• Vapor Pressure: 337mmHg at 25°C
• Melting Point: 84-87 °C(lit.)
• Boiling Point: 46.3 °C at 760 mmHg
• Flash Point: 16.8 °C
• PSA: 49.87000
• LogP: 1.15420
• Storage Temp.: 2-8°C
• Sensitive.: Hygroscopic
• Solubility.: Soluble in Ethanol.
• Water Solubility.: almost transparency
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 80.0141259
• Heavy Atom Count: 4
• Complexity: 10.3

Purity/Quality:

99% ^*data from raw suppliers

Formamidine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=N)N.Cl
• Uses: 5-Methyl-4,6-dihydroxypyrimidine was synthesized from formamidine hydrochloride. N-Formimino-n-glutamate was synthesized from formamidine hydrochloride. Formamidine hydrochloride was used in the synthesis of imidazoleglycerol phosphate (IGP).

Technology Process of Formamidine hydrochloride

There total 17 articles about Formamidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

1,3,5-Triazine (290-87-9) + (E)-3-Methylamino-but-2-enoic acid ethyl ester; hydrochloride → formamidine hydrochloride (6313-33-3) + ethyl 4-methylpyrimidine-5-carboxylate (110960-73-1) + 4-Methylamino-nicotinic acid ethyl ester

Guidance literature:

In acetonitrile; for 6h; Product distribution; Mechanism; Heating; further N-substituted enaminone hydrochlorides;

Reference yield: 38.0%

1,3,5-Triazine (290-87-9) + (E)-3-Ethylamino-but-2-enoic acid ethyl ester; hydrochloride → formamidine hydrochloride (6313-33-3) + ethyl 4-methylpyrimidine-5-carboxylate (110960-73-1) + 4-Ethylamino-nicotinic acid ethyl ester (110960-70-8)

Guidance literature:

In acetonitrile; for 6h; Heating;

Reference yield: 33.0%

1,3,5-Triazine (290-87-9) + (E)-3-Piperidin-1-yl-but-2-enoic acid ethyl ester; hydrochloride → formamidine hydrochloride (6313-33-3) + ethyl 4-methylpyrimidine-5-carboxylate (110960-73-1) + 3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-3'-carboxylic acid ethyl ester

Guidance literature:

In acetonitrile; for 6h; Heating;

upstream raw materials:

1,3,5-Triazine

trichloroacetamidine hydrochloride

acetonitrile

ethanol

Downstream raw materials:

N-formimidoyl-L-leucine

1,3,4-thiadiazol-5-amine

2-phenyl-1,3,5-triazine

2,4-diphenyl-1,3,5-triazine

Refernces

• 1、 -. "HIGHLY TUNABLE COLLOIDAL PEROVSKITE NANOPLATELETS". Paragraph 0074; 0075; 0076. . Retrieved 2017/11/29.
• 2、 Polyakova, Svetlana M.,Kunetskiy, Roman A.,Schroeder, Detlef. "Stabilities of immonium ions derived from N-heterocyclic carbenes probed by collision-induced dissociation mass spectrometry". experimental part. p. 3852 - 3862. Retrieved 2012/09/21.