2-[(E)-2-(4-nitrophenyl)vinyl]pyridine

Base Information

• Chemical Name: 2-[(E)-2-(4-nitrophenyl)vinyl]pyridine
• CAS No.: 1023-67-2
• Molecular Formula: C13H10 N2 O2
• Molecular Weight: 226.235
• Hs Code.: 2933399090
• NSC Number: 42663
• DSSTox Substance ID: DTXSID501347816
• Nikkaji Number: J187.527B,J303.379A
• Wikidata: Q63399186
• Mol file: 1023-67-2.mol

Synonyms:2-[(E)-2-(4-nitrophenyl)vinyl]pyridine;24470-06-2;1023-67-2;2-[(E)-2-(4-Nitrophenyl)ethenyl]pyridine;2-(4-Nitrostyryl)pyridine;2-[(1E)-2-(4-nitrophenyl)ethenyl]pyridine;(E)-2-(4-Nitrostyryl)pyridine;NSC42663;4'-Nitro-2-stilbazole;2-(4'-nitrostyryl)pyridine;SCHEMBL9058120;2-(4-Nitro-trans-styryl)pyridine;DTXSID501347816;MFCD00040365;NSC-42663;AKOS000359316;LS-07688;CS-0335642;2-[(E)-2-(4-Nitrophenyl)ethenyl]pyridine #;2-(2-(4-NITRO-PHENYL)-VINYL)-PYRIDINE;Pyridine, 2-(2-(4-nitrophenyl)ethenyl)- trans;SR-01000319377;2-(2-(4-NITROPHENYL)-TRANS-VINYL)PYRIDINE;SR-01000319377-1;Q63399186

Chemical Property of 2-[(E)-2-(4-nitrophenyl)vinyl]pyridine

Chemical Property:

• Vapor Pressure: 6.17E-05mmHg at 25°C
• Boiling Point: 356°Cat760mmHg
• Flash Point: 169.1°C
• PSA: 58.71000
• Density: 1.273g/cm³
• LogP: 3.68340
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 226.074227566
• Heavy Atom Count: 17
• Complexity: 278

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)C=CC2=CC=C(C=C2)[N+](=O)[O-]
• Isomeric SMILES: C1=CC=NC(=C1)/C=C/C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 2-[(E)-2-(4-nitrophenyl)vinyl]pyridine

There total 5 articles about 2-[(E)-2-(4-nitrophenyl)vinyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

→ 2-(4-nitrostyryl)pyridine (1023-67-2)

Guidance literature:

With C₁₆H₄₁B₁₀ClFeP₂; potassium carbonate; In toluene; at 20 ℃; for 5h;

Reference yield: 90.0%

α-picoline (109-06-8) + 4-nitrobenzaldehdye (555-16-8) → 2-(4-nitrostyryl)pyridine (1023-67-2)

Guidance literature:

With acetic anhydride; acetic acid; calcium chloride; for 24h; Reflux;

Reference yield: 50.8%

4-nitrobenzaldehdye (555-16-8) + 2-picoline boron trifluoride complex → 2-(4-nitrostyryl)pyridine (1023-67-2)

Guidance literature:

In acetic anhydride; at 140 ℃; for 0.5h;

upstream raw materials:

α-picoline

4-nitrobenzaldehdye

pyridine-2-carbaldehyde

diethyl p-nitrobenzylphosphonate

Downstream raw materials:

N-[2-Nitro-4-(2-pyridin-2-yl-ethyl)-phenyl]-acetamide

2-[2-{4-(3-Ethylthioureido)phenyl}ethyl]pyridine

N-[4-(2-Pyridin-2-yl-ethyl)-phenyl]-acetamide

2-<2-(3,4-diaminophenyl)ethyl>pyridine

Refernces

• 1、 Nguyen, Thanh Binh,Nguyen, Tuan Minh,Retailleau, Pascal. "[2+2] Photodimerization of Stilbazoles Promoted by Oxalic Acid in Suspension". supporting information. p. 4682 - 4689. Retrieved 2020/04/15.
• 2、 Hu, Chen-Yu,Li, Xiang,Liang, Xin-Shen,Liu, Ning,Tian, Jun-Jie,Tu, Xian-Shuang,Wang, Xiao-Chen,Yang, Zhao-Ying. "Borane-Catalyzed Chemoselective and Enantioselective Reduction of 2-Vinyl-Substituted Pyridines". supporting information. p. 18452 - 18456. Retrieved 2020/08/21.