4,4'-Dipyridylmethane

Base Information

• Chemical Name: 4,4'-Dipyridylmethane
• CAS No.: 60776-05-8
• Molecular Formula: C11H10 N2
• Molecular Weight: 170.214
• DSSTox Substance ID: DTXSID30209600
• Nikkaji Number: J645.606E
• Wikidata: Q83083948
• Mol file: 60776-05-8.mol

Synonyms:4,4'-dipyridylmethane;4,4'-methylenebis(pyridine)

Chemical Property of 4,4'-Dipyridylmethane

Chemical Property:

• Melting Point: 36-37 °C(Solv: benzene (71-43-2))
• Boiling Point: 316.4±22.0 °C(Predicted)
• PKA: 5.79±0.10(Predicted)
• Flash Point: 119.6oC
• PSA: 25.78000
• Density: 1.096±0.06 g/cm3(Predicted)
• LogP: 2.06740
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 170.084398327
• Heavy Atom Count: 13
• Complexity: 119

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=CC=C1CC2=CC=NC=C2

Technology Process of 4,4'-Dipyridylmethane

There total 5 articles about 4,4'-Dipyridylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4,4'-dipyridyl ketone oxime (58088-22-5) → γ,γ'-dipyridylmethane (60776-05-8)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol; for 2h; Ambient temperature;

Reference yield: 11.0%

picoline (108-89-4) + 4-Chloropyridine (626-61-9) → γ,γ'-dipyridylmethane (60776-05-8)

Guidance literature:

With potassium amide; In diethyl ether; ammonia; at -78 - -75 ℃; for 3h;

DOI:10.1021/ja00300a019

Reference yield:

picoline (108-89-4) + 4-bromopyridine hydrochloride (19524-06-2) → pyridin-3-ylamine (462-08-8) + 4-aminopyridine (504-24-5) + γ,γ'-dipyridylmethane (60776-05-8) + 1,2-bis(4'-pyridyl)ethane (4916-57-8)

Guidance literature:

With ammonia; In diethyl ether; for 0.25h; Irradiation;

DOI:10.1021/jo00162a020

upstream raw materials:

di-pyridin-4-yl-methanone

picoline

4-Chloropyridine

4-bromopyridine hydrochloride

Downstream raw materials:

(Zn(II))2(gable porphyrin)(DPM)

1,1,2,2-tetra(pyridin-4-yl)ethene

Zn(II)(TPP)(DPM)

Refernces

• 1、 Balicki, Roman. "MILD AND SIMPLE HYDROGENATION OF DIARYL OXIMES TO HYDROCARBONS USING AMMONIUM FORMATE-PALLADIUM ON CARBON". . p. 133 - 134. Retrieved 2007/10/02.