6-Methoxy-2,3-dihydro-1H-indene-1-carboxylic acid

Base Information

Chemical Name:6-Methoxy-2,3-dihydro-1H-indene-1-carboxylic acid
CAS No.:62956-62-1
Molecular Formula:C11H12O3
Molecular Weight:192.21
Hs Code.:2918990090
European Community (EC) Number:829-833-5
DSSTox Substance ID:DTXSID50978801
Mol file:62956-62-1.mol

Synonyms:6-Methoxy-2,3-dihydro-1H-indene-1-carboxylic acid;62956-62-1;BRN 2645382;6-METHOXYINDANE-1-CARBOXYLIC ACID;1H-Indene-1-carboxylic acid, 2,3-dihydro-6-methoxy-;6-methoxyindan-1-carboxylic acid;4-10-00-01040 (Beilstein Handbook Reference);SCHEMBL1842495;DTXSID50978801;NYAXSJZIUOHLMW-UHFFFAOYSA-N;6-Methoxy-indane-1-carboxylic acid;AKOS017516283;AB09851;LS-81637;CS-0237243;EN300-180738;F83160;6-Methoxy-2,3-dihydro-1H-indene-1-carboxylicacid;Z1255391179

Suppliers and Price of 6-Methoxy-2,3-dihydro-1H-indene-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-methoxy-2,3-dihydro-1H-indene-1-carboxylicAcid
25mg
$ 45.00

American Custom Chemicals Corporation
6-METHOXYINDANE-1-CARBOXYLIC ACID 95.00%
5MG
$ 503.75

AK Scientific
6-Methoxy-2,3-dihydro-1H-indene-1-carboxylicacid
2.5g
$ 864.00

Total 5 raw suppliers

Chemical Property of 6-Methoxy-2,3-dihydro-1H-indene-1-carboxylic acid

Chemical Property:

Vapor Pressure:9.85E-06mmHg at 25°C
Melting Point:107 - 110°C
Boiling Point:357.5°C at 760 mmHg
Flash Point:143.2°C
PSA：46.53000
Density:1.241g/cm³
LogP:1.80960
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly, Sonicated)
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:192.078644241
Heavy Atom Count:14
Complexity:227

Purity/Quality:

98%min ^*data from raw suppliers

6-methoxy-2,3-dihydro-1H-indene-1-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(CCC2C(=O)O)C=C1

Technology Process of 6-Methoxy-2,3-dihydro-1H-indene-1-carboxylic acid

There total 10 articles about 6-Methoxy-2,3-dihydro-1H-indene-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 134111-83-4
2-(6-methoxy-2,3-dihydro-1H-inden-1-ylidene)-1,3-dithiane

: 62956-62-1
6-methoxy-1-indane-carboxylic acid

Guidance literature:: With hydrogenchloride; acetic acid; for 3h; Heating;
DOI:10.1021/jo00014a033

Reference yield: 70.0%

: 17825-44-4
3-Carboxy-5-methoxy-indanon

: 62956-62-1
6-methoxy-1-indane-carboxylic acid

Guidance literature:: With triethylsilane; trifluoroacetic acid; at 40 ℃; for 4h;
DOI:10.3184/174751911X13057348859515

Reference yield:

: 13623-25-1
6-methoxy-2,3-dihydro-1H-inden-1-one

: 62956-62-1
6-methoxy-1-indane-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1. n-BuLi / 1. THF, hexane, -15 deg C, 2 h 2. 0 deg C, 30 h

2: 97 percent / p-TsOH*H₂O / benzene / 1 h

3: 100 percent / glac. HOAc, conc. HCl / 3 h / Heating

With hydrogenchloride; n-butyllithium; toluene-4-sulfonic acid; acetic acid; In benzene;
DOI:10.1021/jo00014a033