5,10-Dihydro-6,7-dimethyl-4H-benzo[5,6]cyclohepta[1,2-b]furan

Base Information

Chemical Name:5,10-Dihydro-6,7-dimethyl-4H-benzo[5,6]cyclohepta[1,2-b]furan
CAS No.:56881-47-1
Molecular Formula:C15H16O
Molecular Weight:212.29
Hs Code.:
Mol file:56881-47-1.mol

Synonyms:7,8-Dimethyl-9,10-dihydro-4H-3-oxa-benzo[f]azulene;pallescensin-E;opt. inakt. Pallesconsin E;

Suppliers and Price of 5,10-Dihydro-6,7-dimethyl-4H-benzo[5,6]cyclohepta[1,2-b]furan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5,10-Dihydro-6,7-dimethyl-4H-benzo[5,6]cyclohepta[1,2-b]furan

Chemical Property:

PSA：13.14000
LogP:3.58580

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5,10-Dihydro-6,7-dimethyl-4H-benzo[5,6]cyclohepta[1,2-b]furan

There total 9 articles about 5,10-Dihydro-6,7-dimethyl-4H-benzo[5,6]cyclohepta[1,2-b]furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78012-22-3
C₂₂H₂₂N₂O₃S

: 56881-47-1
pallescensin E

Guidance literature:: With sodium cyanoborohydride; In N,N-dimethyl-formamide; at 120 ℃; for 12h;
DOI:10.1039/P19810003087

Reference yield:

: 5724-56-1
2,3-dimethylbenzonitrile

: 56881-47-1
pallescensin E

Guidance literature:: Multi-step reaction with 10 steps

1: 96 percent / aq. potassium hydroxide

2: 62 percent / lithium aluminium hydride / tetrahydrofuran

3: 98 percent / pyridinium chlorochromate / CH₂Cl₂

4: 45 percent / sodium hydride, 15-crown-5 / bis-(2-methoxy-ethyl) ether / 1) 80 deg C, 1.5 h; 2) room temperature, 1 h

5: 54 percent / hydrogen, chlorotris(triphenylphosphine)rhodium / ethanol; benzene / 336 h / 70 °C / 121600 Torr

6: 69 percent / aq. sodium hydroxide / ethanol / 1 h / Heating

7: thionyl chloride / benzene / 2 h / Heating

8: 7.52 g / aluminium chloride / nitrobenzene / 1) room temperature, 16 h; 2) 80 deg C, 4 h

9: toluene-4-sulphonic acid / ethanol / 16 h / 80 °C

10: 290 mg / sodium cyanotrihydridoborate / dimethylformamide / 12 h / 120 °C

With potassium hydroxide; sodium hydroxide; Wilkinson's catalyst; lithium aluminium tetrahydride; aluminium trichloride; thionyl chloride; 15-crown-5; hydrogen; sodium hydride; sodium cyanoborohydride; toluene-4-sulfonic acid; pyridinium chlorochromate; In tetrahydrofuran; ethanol; dichloromethane; diethylene glycol dimethyl ether; nitrobenzene; N,N-dimethyl-formamide; benzene;
DOI:10.1039/P19810003087

Reference yield:

: 5779-93-1
2,3-dimethylbenzaldehyde

: 56881-47-1
pallescensin E

Guidance literature:: Multi-step reaction with 7 steps

1: 45 percent / sodium hydride, 15-crown-5 / bis-(2-methoxy-ethyl) ether / 1) 80 deg C, 1.5 h; 2) room temperature, 1 h

2: 54 percent / hydrogen, chlorotris(triphenylphosphine)rhodium / ethanol; benzene / 336 h / 70 °C / 121600 Torr

3: 69 percent / aq. sodium hydroxide / ethanol / 1 h / Heating

4: thionyl chloride / benzene / 2 h / Heating

5: 7.52 g / aluminium chloride / nitrobenzene / 1) room temperature, 16 h; 2) 80 deg C, 4 h

6: toluene-4-sulphonic acid / ethanol / 16 h / 80 °C

7: 290 mg / sodium cyanotrihydridoborate / dimethylformamide / 12 h / 120 °C

With sodium hydroxide; Wilkinson's catalyst; aluminium trichloride; thionyl chloride; 15-crown-5; hydrogen; sodium hydride; sodium cyanoborohydride; toluene-4-sulfonic acid; In ethanol; diethylene glycol dimethyl ether; nitrobenzene; N,N-dimethyl-formamide; benzene;
DOI:10.1039/P19810003087