Einecs 274-134-5

Base Information

Chemical Name:Einecs 274-134-5
CAS No.:69822-83-9
Molecular Formula:C62H58 Cl2 N6 O17 P2
Molecular Weight:1292.03
Hs Code.:
European Community (EC) Number:274-134-5
DSSTox Substance ID:DTXSID901100315
Nikkaji Number:J342.583E

Synonyms:EINECS 274-134-5;69822-83-9;3'-Cytidylic acid, 5'-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(4-chlorophenyl)thymidylyl-(3'.5')-N-benzoyl-2'-deoxy-, 4-chlorophenyl 2-cyanoethyl ester;DTXSID901100315;3'-Cytidylic acid, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)thymidylyl-(3'-->5')-N-benzoyl-2'-deoxy-, 4-chlorophenyl 2-cyanoethyl ester

Suppliers and Price of Einecs 274-134-5

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Einecs 274-134-5

Chemical Property:

XLogP3:8.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:26
Exact Mass:1290.2710738
Heavy Atom Count:89
Complexity:2640

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN(C(=O)NC1=O)C2CC(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(=O)(OCC6C(CC(O6)N7C=CC(=NC7=O)NC(=O)C8=CC=CC=C8)OP(=O)(OCCC#N)OC9=CC=C(C=C9)Cl)OC1=CC=C(C=C1)Cl
Isomeric SMILES:CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(=O)(OC[C@@H]6[C@H](C[C@@H](O6)N7C=CC(=NC7=O)NC(=O)C8=CC=CC=C8)OP(=O)(OCCC#N)OC9=CC=C(C=C9)Cl)OC1=CC=C(C=C1)Cl

Technology Process of Einecs 274-134-5

There total 4 articles about Einecs 274-134-5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71100-57-7
C₃₇H₃₅ClN₂O₁₀P^(1-)

: 69822-83-9
5'-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(4-chlorophenyl)thymidylyl-(3'->5')-N-benzoyl-2'-deoxy-3'-cytidylic acid, 4-chlorophenyl 2-cyanoethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1-(mesitylsulfonyl)tetrazole / pyridine / 1 h / Ambient temperature

2: 1-methylimidazole / pyridine; acetonitrile / 1 h / Ambient temperature

With 1-methyl-1H-imidazole; 1-mesitylsulfonyl-1H-tetrazole; In pyridine; acetonitrile;

Reference yield:

: 62420-37-5
(p-chlorophenyl) di(1,2,4-triazolido)phosphate

: 69822-83-9
5'-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(4-chlorophenyl)thymidylyl-(3'->5')-N-benzoyl-2'-deoxy-3'-cytidylic acid, 4-chlorophenyl 2-cyanoethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) pyridine; 2.) 5percent aq. NH₄HCO₃ / 1.) dioxane, 30 min at room temp.; 2.) dioxane, cooling

2: 1-(mesitylsulfonyl)tetrazole / pyridine / 1 h / Ambient temperature

3: 1-methylimidazole / pyridine; acetonitrile / 1 h / Ambient temperature

With pyridine; 1-methyl-1H-imidazole; 1-mesitylsulfonyl-1H-tetrazole; ammonium bicarbonate; In pyridine; acetonitrile;

Reference yield:

: 40615-39-2
5'-O-(4-4'-dimethoxytrityl)thymidine

: 69822-83-9
5'-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(4-chlorophenyl)thymidylyl-(3'->5')-N-benzoyl-2'-deoxy-3'-cytidylic acid, 4-chlorophenyl 2-cyanoethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) pyridine; 2.) 5percent aq. NH₄HCO₃ / 1.) dioxane, 30 min at room temp.; 2.) dioxane, cooling

2: 1-(mesitylsulfonyl)tetrazole / pyridine / 1 h / Ambient temperature

3: 1-methylimidazole / pyridine; acetonitrile / 1 h / Ambient temperature

With pyridine; 1-methyl-1H-imidazole; 1-mesitylsulfonyl-1H-tetrazole; ammonium bicarbonate; In pyridine; acetonitrile;