4-((Dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole

Base Information

Chemical Name:4-((Dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole
CAS No.:73425-59-9
Molecular Formula:C₁₄H₁₈N₂S
Molecular Weight:246.376
Hs Code.:
DSSTox Substance ID:DTXSID20994159
Mol file:73425-59-9.mol

Synonyms:BRN 0615082;73425-59-9;4-((Dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole;N,N-Dimethyl-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole-4-methylamine;Thiopyrano(2,3-b)indole, 2,3,4,9-tetrahydro-4-((dimethylamino)methyl)-;Thiopyrano(2,3-b)indole-4-methylamine, 2,3,4,9-tetrahydro-N,N-dimethyl-;N,N-dimethyl-1-(2,3,4,9-tetrahydrothiopyrano[2,3-b]indol-4-yl)methanamine;SCHEMBL11384705;DTXSID20994159;UWJHHSFHADDLQF-UHFFFAOYSA-N;LS-153285;4-Dimethylaminomethyl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole

Suppliers and Price of 4-((Dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N,N-DIMETHYL-2,3,4,9-TETRAHYDROTHIOPYRANO(2,3-B)INDOLE-4-METHYLAMINE 95.00%
5MG
$ 505.92

Total 0 raw suppliers

Chemical Property of 4-((Dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole

Chemical Property:

Vapor Pressure:1.86E-06mmHg at 25°C
Boiling Point:395.3°C at 760 mmHg
Flash Point:192.8°C
PSA：44.33000
Density:1.175g/cm³
LogP:3.30890
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:246.11906976
Heavy Atom Count:17
Complexity:269

Purity/Quality:: N,N-DIMETHYL-2,3,4,9-TETRAHYDROTHIOPYRANO(2,3-B)INDOLE-4-METHYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CC1CCSC2=C1C3=CC=CC=C3N2

Technology Process of 4-((Dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole

There total 12 articles about 4-((Dimethylamino)methyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 73425-08-8
2,3,4,9-tetrahydrothiopyrano<2,3-b>indole-4-carbaldehyde

: 73425-59-9
4-(N,N-dimethylaminomethyl)-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

Guidance literature:: With sodium hydroxide; formic acid; dimethyl amine; In methanol; benzene;

Reference yield: 66.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 73425-49-7
4-aminomethyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

: 73425-59-9
4-(N,N-dimethylaminomethyl)-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

Guidance literature:: With sodium hydroxide; sodium cyanoborohydride; acetic acid; In tetrahydrofuran;

Reference yield:

: 59-48-3
2-oxoindole

: 73425-59-9
4-(N,N-dimethylaminomethyl)-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

Guidance literature:: Multi-step reaction with 4 steps

1: P₂S₅

2: K₂CO₃ / acetone / 5 h / Ambient temperature

3: pyridine / 2 h / 100 °C

4: 1) 98 percent HCOOH / 1.) MeOH, RT; 2.) benzene, DMF, reflux, 1 h

With formic acid; tetraphosphorus decasulfide; potassium carbonate; In pyridine; acetone;
DOI:10.1248/cpb.32.872