8-Chloroquinoline

Base Information

Chemical Name:8-Chloroquinoline
CAS No.:611-33-6
Molecular Formula:C9H6ClN
Molecular Weight:163.606
Hs Code.:29334900
European Community (EC) Number:210-265-6
NSC Number:56815
UNII:U4UPA3J2CR
DSSTox Substance ID:DTXSID9060601
Nikkaji Number:J95.377F
Wikidata:Q27121421
Metabolomics Workbench ID:57152
Mol file:611-33-6.mol

Synonyms:8-chloroquinoline

Suppliers and Price of 8-Chloroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
8-Chloroquinoline >98.0%(GC)
5g
$ 129.00

TCI Chemical
8-Chloroquinoline >98.0%(GC)
25g
$ 428.00

SynQuest Laboratories
8-Chloroquinoline
100 g
$ 501.00

SynQuest Laboratories
8-Chloroquinoline
25 g
$ 164.00

Sigma-Aldrich
8-Chloroquinoline AldrichCPR
100mg
$ 57.00

Frontier Specialty Chemicals
8-Chloroquinoline 99%
10g
$ 209.00

Crysdot
8-Chloroquinoline 98%
100g
$ 238.00

Chem-Impex
8-Chloroquinoline,≥98%(GC) ≥98%(GC)
5G
$ 148.04

Chemenu
8-Chloroquinoline 98%
100g
$ 224.00

Biosynth Carbosynth
8-chloroquinoline
5 g
$ 90.00

Total 80 raw suppliers

Chemical Property of 8-Chloroquinoline

Chemical Property:

Appearance/Colour:Clear yellow to brown liquid
Vapor Pressure:0.00404mmHg at 25°C
Melting Point:-20 °C
Refractive Index:1.652
Boiling Point:288.5 °C at 760 mmHg
PKA:2.33±0.17(Predicted)
Flash Point:145.2 °C
PSA：12.89000
Density:1.27 g/cm³
LogP:2.88820
Storage Temp.:Inert atmosphere,Room Temperature
Water Solubility.:SOLUBLE
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:163.0188769
Heavy Atom Count:11
Complexity:138

Purity/Quality:

99% ^*data from raw suppliers

8-Chloroquinoline >98.0%(GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,T
Statements: 36/37/38-25
Safety Statements: 37/39-26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)Cl)N=CC=C2

Technology Process of 8-Chloroquinoline

There total 13 articles about 8-Chloroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 95-51-2
o-chloroaniline

: 56-81-5,25618-55-7,64333-26-2,8013-25-0
glycerol

: 611-33-6
8-chloroquinoline

Guidance literature:: o-chloroaniline; glycerol; With ferrous(II) sulfate heptahydrate; methanesulfonic acid; sodium 3-nitrobenzenesulfonate; at 125 ℃; for 18.5h;

With potassium hydroxide; In water; pH=14; Cooling with ice;
DOI:10.1021/ol201539d

Reference yield: 78.0%

: 137-04-2
2-chloroaniline hydrochloride

: 56-81-5,25618-55-7,64333-26-2,8013-25-0
glycerol

: 611-33-6
8-chloroquinoline

Guidance literature:: With sulfuric acid; iron(II) sulfate; In nitrobenzene; at 80 ℃; for 5h;
DOI:10.1016/j.tet.2005.07.043

Reference yield: 75.0%

: 4470-83-1
2,8-dichloroquinoline

: 611-33-6
8-chloroquinoline

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; at 25 ℃; for 6h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.molcata.2014.06.012