2,9-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol

Base Information

Chemical Name:2,9-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol
CAS No.:25651-04-1
Molecular Formula:C19H21 N O4
Molecular Weight:327.38
Hs Code.:
Nikkaji Number:J3.170.283F
Wikidata:Q105210860
Pharos Ligand ID:XRK8QP3A3D7A
ChEMBL ID:CHEMBL410604
Mol file:25651-04-1.mol

Synonyms:bracteoline

Suppliers and Price of 2,9-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 12 raw suppliers

Chemical Property of 2,9-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol

Chemical Property:

Vapor Pressure:9.55E-12mmHg at 25°C
Boiling Point:527.5°Cat760mmHg
Flash Point:272.9°C
Density:1.29g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:327.14705815
Heavy Atom Count:24
Complexity:461

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC2=CC(=C(C3=C2C1CC4=CC(=C(C=C43)O)OC)O)OC

Technology Process of 2,9-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol

There total 5 articles about 2,9-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,10-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 475-81-0
glaucine

: 3019-51-0,5164-93-2,13529-67-4,104597-61-7
isoboldine

: 25651-04-1
bracteoline

: 1418137-71-9
11-sulfonyl-1,11-anhydrobracteoline

: 5083-88-5,20068-96-6
thaliporphine

Guidance literature:: With sulfuric acid; In water; at 20 ℃; for 312h;
DOI:10.1021/np3007765

Reference yield:

: 371196-15-5
N-formyl-laurolitsine

: 3019-51-0,5164-93-2,13529-67-4,104597-61-7
isoboldine

: 25651-04-1
bracteoline

: 1418137-71-9
11-sulfonyl-1,11-anhydrobracteoline

: 5083-88-5,20068-96-6
thaliporphine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / methanol / 24 h / 70 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere; Reflux

3: sulfuric acid / water / 312 h / 20 °C

With lithium aluminium tetrahydride; sulfuric acid; potassium carbonate; In tetrahydrofuran; methanol; water;
DOI:10.1021/np3007765

Reference yield:

: 5890-18-6,568-39-8
(+)-norboldine

: 3019-51-0,5164-93-2,13529-67-4,104597-61-7
isoboldine

: 25651-04-1
bracteoline

: 1418137-71-9
11-sulfonyl-1,11-anhydrobracteoline

: 5083-88-5,20068-96-6
thaliporphine

Guidance literature:: Multi-step reaction with 4 steps

1: N,N-dimethyl-formamide / 60 h / 90 °C / Sealed tube

2: potassium carbonate / methanol / 24 h / 70 °C

3: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere; Reflux

4: sulfuric acid / water / 312 h / 20 °C

With lithium aluminium tetrahydride; sulfuric acid; potassium carbonate; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
DOI:10.1021/np3007765