N-(7-Hydroxy-1-naphthyl)benzamide

Base Information

• Chemical Name: N-(7-Hydroxy-1-naphthyl)benzamide
• CAS No.: 6361-30-4
• Molecular Formula: C17H13 N O2
• Molecular Weight: 263.296
• Hs Code.: 2924299090
• European Community (EC) Number: 228-834-2
• DSSTox Substance ID: DTXSID90212993
• Nikkaji Number: J206.958J
• Wikidata: Q83088230
• Mol file: 6361-30-4.mol

Synonyms:N-(7-Hydroxy-1-naphthyl)benzamide;N-(7-hydroxynaphthalen-1-yl)benzamide;6361-30-4;EINECS 228-834-2;SCHEMBL5694477;DTXSID90212993;AKOS024343328;Benzamide, N-(7-hydroxy-1-naphthyl)-;Benzamide, N-(7-hydroxy-1-naphthalenyl)-;N-(7-HYDROXY-NAPHTHALEN-1-YL)-BENZAMIDE

Chemical Property of N-(7-Hydroxy-1-naphthyl)benzamide

Chemical Property:

• Vapor Pressure: 5.98E-07mmHg at 25°C
• Boiling Point: 399.4°C at 760 mmHg
• Flash Point: 195.3°C
• PSA: 52.82000
• Density: 1.31g/cm³
• LogP: 4.18170
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 263.094628657
• Heavy Atom Count: 20
• Complexity: 338

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NC2=CC=CC3=C2C=C(C=C3)O

Technology Process of N-(7-Hydroxy-1-naphthyl)benzamide

There total 2 articles about N-(7-Hydroxy-1-naphthyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

8-amino-2-naphthol (118-46-7) + benzoyl chloride (98-88-4) → N-7-(hydroxynaphthalen-1-yl)benzamide (6361-30-4)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1002/chem.201201032

Reference yield:

8-amino-2-naphthol (118-46-7) + benzoyl chloride (98-88-4) → N-7-(hydroxynaphthalen-1-yl)benzamide (6361-30-4) + 1-benzoylamino-7-benzoyloxy-naphthalene

Guidance literature:

With pyridine; benzene;

Reference yield: 80.0%

N-7-(hydroxynaphthalen-1-yl)benzamide (6361-30-4) + (S)-(1,1'-binaphthyl-2,2'-dioxy)chlorophosphine → N-(7-((11bS)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yloxy)naphthalen-1-yl)benzamide

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1002/chem.201201032

upstream raw materials:

8-amino-2-naphthol

benzoyl chloride