4-(4-Methoxyphenoxy)benzoyl chloride

Base Information

Chemical Name:4-(4-Methoxyphenoxy)benzoyl chloride
CAS No.:68548-50-5
Molecular Formula:C14H11ClO3
Molecular Weight:262.693
Hs Code.:
DSSTox Substance ID:DTXSID10988224
Wikidata:Q82976701

Synonyms:4-(4-Methoxyphenoxy)benzoyl chloride;Benzoyl chloride, 4-(4-methoxyphenoxy)-;68548-50-5;SCHEMBL11511850;DTXSID10988224

Suppliers and Price of 4-(4-Methoxyphenoxy)benzoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-(4-Methoxyphenoxy)benzoyl chloride

Chemical Property:

Vapor Pressure:1.14E-05mmHg at 25°C
Boiling Point:370°Cat760mmHg
Flash Point:149.5°C
Density:1.248g/cm³
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:262.0396719
Heavy Atom Count:18
Complexity:266

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)Cl

Technology Process of 4-(4-Methoxyphenoxy)benzoyl chloride

There total 4 articles about 4-(4-Methoxyphenoxy)benzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3525-22-2
4'-(4-methoxyphenoxy)benzoic acid

: 68548-50-5
4-(4-methoxy-phenoxy)-benzoyl chloride

Guidance literature:: With thionyl chloride; In benzene;

Reference yield:

: 104-94-9
4-methoxy-aniline

: 68548-50-5
4-(4-methoxy-phenoxy)-benzoyl chloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: sulfuric acid; sodium nitrite / water / 2 h / 0 °C

1.2: 16 h / 0 - 20 °C

2.1: copper(l) iodide; dimethylaminoacetic acid; caesium carbonate / 1,4-dioxane / 24 h / 110 °C / Inert atmosphere

3.1: sodium hydroxide / ethanol / 3 h / 80 °C / Reflux

4.1: thionyl chloride; pyridine / acetonitrile / 6 h / 75 °C / Reflux

With pyridine; copper(l) iodide; thionyl chloride; dimethylaminoacetic acid; sulfuric acid; caesium carbonate; sodium hydroxide; sodium nitrite; In 1,4-dioxane; ethanol; water; acetonitrile; 2.1: |Ullmann Condensation;
DOI:10.1016/j.cclet.2015.06.017

Reference yield:

: 696-62-8
para-iodoanisole

: 68548-50-5
4-(4-methoxy-phenoxy)-benzoyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: copper(l) iodide; dimethylaminoacetic acid; caesium carbonate / 1,4-dioxane / 24 h / 110 °C / Inert atmosphere

2: sodium hydroxide / ethanol / 3 h / 80 °C / Reflux

3: thionyl chloride; pyridine / acetonitrile / 6 h / 75 °C / Reflux

With pyridine; copper(l) iodide; thionyl chloride; dimethylaminoacetic acid; caesium carbonate; sodium hydroxide; In 1,4-dioxane; ethanol; acetonitrile; 1: |Ullmann Condensation;
DOI:10.1016/j.cclet.2015.06.017